Demethylcantharidate disodium
Modify Date: 2024-01-28 16:53:49
Demethylcantharidate disodium structure
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Common Name | Demethylcantharidate disodium | ||
|---|---|---|---|---|
| CAS Number | 129-67-9 | Molecular Weight | 230.13 | |
| Density | N/A | Boiling Point | 447.8ºC at 760 mmHg | |
| Molecular Formula | C8H8Na2O5 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | 190.5ºC | |
Use of Demethylcantharidate disodiumDemethylcantharidate disodium, an endogenous metabolite, induces apoptosis in hepatocellular carcinoma cells via ER stress. Demethylcantharidate disodium shows excellent anticancer activity against multiple types of cancer[1]. |
| Name | endothal-disodium |
|---|---|
| Synonym | More Synonyms |
| Description | Demethylcantharidate disodium, an endogenous metabolite, induces apoptosis in hepatocellular carcinoma cells via ER stress. Demethylcantharidate disodium shows excellent anticancer activity against multiple types of cancer[1]. |
|---|---|
| Related Catalog | |
| In Vitro | Demethylcantharidate (0-100 μM; 0, 12, 24, 48 or 72 hours) disodium inhibits HCC cell proliferation[1]. Demethylcantharidate (0, 9, 18 or 36 µM; 24 hours) disodium dose dependently increases the levels of cleaved caspase-3, cleaved caspase-9, and Bax/Bcl-2[1]. Cell Viability Assay[1] Cell Line: HCC cell lines (SMMC-7721 and Bel-7402) Concentration: 0-100 μM Incubation Time: 0, 12, 24, 48 or 72 hours Result: Showed anti-proliferative activity in the two HCC cell lines. Cell Viability Assay[1] Cell Line: HCC cells Concentration: 0, 9, 18 or 36 µM Incubation Time: 24 hours Result: Induced apoptosis in HCC cells via the intrinsic pathway. |
| In Vivo | Demethylcantharidate disodium significantly decreases hepatocellular carcinoma tumorigenesis of SMMC-7721 cells in vivo[1]. |
| References |
| Boiling Point | 447.8ºC at 760 mmHg |
|---|---|
| Molecular Formula | C8H8Na2O5 |
| Molecular Weight | 230.13 |
| Flash Point | 190.5ºC |
| Exact Mass | 230.01700 |
| PSA | 89.49000 |
| Vapour Pressure | 2.88E-09mmHg at 25°C |
| Risk Phrases | 21-25-36/37/38 |
|---|---|
| RIDADR | UN 2588 |
| Packaging Group | II |
| Hazard Class | 6.1(a) |
| Precursor 1 | |
|---|---|
| DownStream 0 | |
CAS#:5442-12-6| disodium 7-oxabicyclo[2.2.1]heptane-2,3-dicarboxylate |
| disodium demethylcantharate |
| endothal |
| disodium,7-oxabicyclo[2.2.1]heptane-2,3-dicarboxylate |
| endothal-sodium |
| Disodium endothall |
| disodium endothallate |
| Accelerate |
| Endothal-sodium |
| Endothal-disodium |
| disodium (1Ξ,2Ξ,3Ξ,4Ξ)-7-oxabicyclo[2.2.1]heptane-2,3-dicarboxylate |
| Endothall sodium |
| Endothall disodium salt |
| Caswell No. 421C |
| endothall sodium |
| Ripenthol |
| Natriicantharidas |
| Aguathol |
- Shanghai Nianxing Industrial Co., Ltd
- China
- Product Name: Demethylcantharidate disodium
- Price: Negotiable
- Purity: 98.0%
- Delivery: 10 Day
- Contact: Huang
- Email: sales@echemcloud.com
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Price: ￥500/10 mg
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