kapurimycin A3

Modify Date: 2024-02-29 09:54:09

kapurimycin A3 Structure
kapurimycin A3 structure
Common Name kapurimycin A3
CAS Number 129966-45-6 Molecular Weight 492.47400
Density 1.49g/cm3 Boiling Point 736.5ºC at 760mmHg
Molecular Formula C27H24O9 Melting Point N/A
MSDS N/A Flash Point 250.4ºC

 Use of kapurimycin A3


Kapurimycin A3 is an antitumor and antibacterial antibiotic. Kapurimycin A3 has DNA binding and breakage activity. Kapurimycin A3 can be isolated from Streptomyces[1][2].

 Names

Name 2-[(8S)-8-acetyloxy-12-hydroxy-2-[(2S,3R)-2-methyl-3-[(Z)-prop-1-enyl]oxiran-2-yl]-4,11-dioxo-9,10-dihydro-8H-naphtho[2,3-h]chromen-5-yl]acetic acid
Synonym More Synonyms

 kapurimycin A3 Biological Activity

Description Kapurimycin A3 is an antitumor and antibacterial antibiotic. Kapurimycin A3 has DNA binding and breakage activity. Kapurimycin A3 can be isolated from Streptomyces[1][2].
Related Catalog
References

[1]. Hara M, et al. Covalent modification and single-strand scission of DNA by a new antitumor antibiotic kapurimycin A3. Biochemistry. 1990 Nov 20;29(46):10449-55.  

[2]. PRODUCING ORGANISM, et al. THE KAPURIMYCINS, NEW ANTITUMOR ANTIBIOTICS PRODUCED BY STREPTOMYCES. The Journal of Antibiotics. 1990. 43 (12), p. 1513-1518

 Chemical & Physical Properties

Density 1.49g/cm3
Boiling Point 736.5ºC at 760mmHg
Molecular Formula C27H24O9
Molecular Weight 492.47400
Flash Point 250.4ºC
Exact Mass 492.14200
PSA 143.64000
LogP 4.04970
Vapour Pressure 8.99E-23mmHg at 25°C
Index of Refraction 1.682

 Synonyms

Kapurimycin A3
4H-Anthra(1,2-b)pyran-5-acetic acid,8-(acetyloxy)-8,9,10,11-tetraahydro-12-hydroxy-2-(2-methyl-3-(1-propenyl)oxiranyl)-4,11-dioxo