Oncaspar

Modify Date: 2024-09-11 20:35:18

Oncaspar Structure
Oncaspar structure
Common Name Oncaspar
CAS Number 130167-69-0 Molecular Weight 418.652
Density 1.1±0.1 g/cm3 Boiling Point 534.2±39.0 °C at 760 mmHg
Molecular Formula C27H46O3 Melting Point N/A
MSDS N/A Flash Point 276.8±27.1 °C

 Use of Oncaspar


Oncaspar (PEG-L-asparaginase; Pegasparaginase), a pegylated form of native Escherichia coli-derived L-asparaginase, breaks down the amino acid asparagine that are circulating in the bloodstream. Oncaspar plays an important role in acute lymphoblastic leukemia (ALL)[1].

 Names

Name (3β,7α)-7-Hydroperoxycholest-5-en-3-ol
Synonym More Synonyms

 Oncaspar Biological Activity

Description Oncaspar (PEG-L-asparaginase; Pegasparaginase), a pegylated form of native Escherichia coli-derived L-asparaginase, breaks down the amino acid asparagine that are circulating in the bloodstream. Oncaspar plays an important role in acute lymphoblastic leukemia (ALL)[1].
Related Catalog
References

[1]. Young-A Heo, et al. Pegaspargase: A Review in Acute Lymphoblastic Leukaemia.Drugs. 2019 May;79(7):767-777.  

 Chemical & Physical Properties

Density 1.1±0.1 g/cm3
Boiling Point 534.2±39.0 °C at 760 mmHg
Molecular Formula C27H46O3
Molecular Weight 418.652
Flash Point 276.8±27.1 °C
Exact Mass 418.344696
LogP 8.83
Vapour Pressure 0.0±3.2 mmHg at 25°C
Index of Refraction 1.536

 Synonyms

(3β,7α)-7-Hydroperoxycholest-5-en-3-ol
Cholest-5-en-3-ol, 7-hydroperoxy-, (3β,7α)-