2,2':5',2''-Terthien-5-ylmethanol

Modify Date: 2024-01-03 19:08:36

2,2':5',2''-Terthien-5-ylmethanol Structure
2,2':5',2''-Terthien-5-ylmethanol structure
Common Name 2,2':5',2''-Terthien-5-ylmethanol
CAS Number 13059-93-3 Molecular Weight 278.41
Density 1.4±0.1 g/cm3 Boiling Point 424.7±40.0 °C at 760 mmHg
Molecular Formula C13H10OS3 Melting Point N/A
MSDS N/A Flash Point 210.6±27.3 °C

 Use of 2,2':5',2''-Terthien-5-ylmethanol


α-Terthienylmethanol is a terthiophene isolated from the n-hexane fraction of E. prostrata. α-Terthienylmethanol has potent cytotoxic activity against human endometrial cancer cells (Hec1A and Ishikawa) (IC50 < 1 μM). α-Terthienylmethanol increases the intracellular level of ROS and decreases that of GSH[1].

 Names

Name [5-(5-thiophen-2-ylthiophen-2-yl)thiophen-2-yl]methanol
Synonym More Synonyms

 2,2':5',2''-Terthien-5-ylmethanol Biological Activity

Description α-Terthienylmethanol is a terthiophene isolated from the n-hexane fraction of E. prostrata. α-Terthienylmethanol has potent cytotoxic activity against human endometrial cancer cells (Hec1A and Ishikawa) (IC50 < 1 μM). α-Terthienylmethanol increases the intracellular level of ROS and decreases that of GSH[1].
Related Catalog
References

[1]. Jae-Seung Lee, et al. α-Terthienylmethanol, isolated from Eclipta prostrata, induces apoptosis by generating reactive oxygen species via NADPH oxidase in human endometrial cancer cells. J Ethnopharmacol. 2015, 169.  

 Chemical & Physical Properties

Density 1.4±0.1 g/cm3
Boiling Point 424.7±40.0 °C at 760 mmHg
Molecular Formula C13H10OS3
Molecular Weight 278.41
Flash Point 210.6±27.3 °C
Exact Mass 277.989380
PSA 104.95000
LogP 4.38
Vapour Pressure 0.0±1.1 mmHg at 25°C
Index of Refraction 1.687

 Safety Information

HS Code 2934999090

 Customs

HS Code 2934999090
Summary 2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

 Synonyms

2,2':5',2''-Terthien-5-ylmethanol
2,2':5',2''-Terthiophen-5-ylmethanol
[2,2':5',2''-Terthiophene]-5-methanol