Aschantin

Modify Date: 2024-01-03 13:15:26

Aschantin structure	Common Name	Aschantin
	CAS Number	13060-15-6	Molecular Weight	400.42
	Density	1.3±0.1 g/cm3	Boiling Point	525.8±50.0 °C at 760 mmHg
	Molecular Formula	C₂₂H₂₄O₇	Melting Point	N/A
	MSDS	N/A	Flash Point	214.7±30.0 °C

Use of Aschantin

Aschantin, a bisepoxylignan, can be isolated from Magnolia biondii. Aschantin has antiplasmodial, Ca2+-antagonistic, platelet activating factor-antagonistic, and chemopreventive activities. Aschantin is a mTOR kinase inhibitor. Aschantin is also an inhibitor of Cytochrome P450 and UGT enzyme[1][2].

Name	(+)-Aschantin
Synonym	More Synonyms

Description	Aschantin, a bisepoxylignan, can be isolated from Magnolia biondii. Aschantin has antiplasmodial, Ca2+-antagonistic, platelet activating factor-antagonistic, and chemopreventive activities. Aschantin is a mTOR kinase inhibitor. Aschantin is also an inhibitor of Cytochrome P450 and UGT enzyme[1][2].
Related Catalog	Signaling Pathways >> PI3K/Akt/mTOR >> mTOR Research Areas >> Cancer Research Areas >> Cardiovascular Disease Research Areas >> Infection Signaling Pathways >> Metabolic Enzyme/Protease >> Cytochrome P450
References	[1]. Lee CJ, et al. Aschantin targeting on the kinase domain of mammalian target of rapamycin suppresses epidermal growth factor-induced neoplastic cell transformation. Carcinogenesis. 2015 Oct;36(10):1223-34. [2]. Kwon SS, et al. Inhibitory Effects of Aschantin on Cytochrome P450 and Uridine 5'-diphospho-glucuronosyltransferase Enzyme Activities in Human Liver Microsomes. Molecules. 2016 Apr 27;21(5):554.

Description

Related Catalog

Signaling Pathways >> PI3K/Akt/mTOR >> mTOR

Research Areas >> Cancer

Research Areas >> Cardiovascular Disease

Research Areas >> Infection

Signaling Pathways >> Metabolic Enzyme/Protease >> Cytochrome P450

References

[1]. Lee CJ, et al. Aschantin targeting on the kinase domain of mammalian target of rapamycin suppresses epidermal growth factor-induced neoplastic cell transformation. Carcinogenesis. 2015 Oct;36(10):1223-34.

[2]. Kwon SS, et al. Inhibitory Effects of Aschantin on Cytochrome P450 and Uridine 5'-diphospho-glucuronosyltransferase Enzyme Activities in Human Liver Microsomes. Molecules. 2016 Apr 27;21(5):554.

Density	1.3±0.1 g/cm3
Boiling Point	525.8±50.0 °C at 760 mmHg
Molecular Formula	C₂₂H₂₄O₇
Molecular Weight	400.42
Flash Point	214.7±30.0 °C
Exact Mass	400.152191
LogP	2.90
Vapour Pressure	0.0±1.3 mmHg at 25°C
Index of Refraction	1.571

(+)-Aschantin

5-[(1S,3aR,4S,6aR)-4-(3,4,5-Trimethoxyphenyl)tetrahydro-1H,3H-furo[3,4-c]furan-1-yl]-1,3-benzodioxole

1,3-Benzodioxole, 5-[(1S,3aR,4S,6aR)-tetrahydro-4-(3,4,5-trimethoxyphenyl)-1H,3H-furo[3,4-c]furan-1-yl]-

Shanghai Nianxing Industrial Co., Ltd
China
Product Name: Aschantin, 98%
Price: Click To Check
Purity: 98.0%
Delivery: 10 Day
Contact: Yang
Email: sales@echemcloud.com

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: Aschantin
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Delivery: Inquiry
Contact: Ms Wang
Email: enquiry@dycnchem.com

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