BMP-22
Modify Date: 2024-04-09 11:31:53
BMP-22 structure
|
Common Name | BMP-22 | ||
|---|---|---|---|---|
| CAS Number | 1306684-90-1 | Molecular Weight | 382.517 | |
| Density | 1.0±0.1 g/cm3 | Boiling Point | 533.2±53.0 °C at 760 mmHg | |
| Molecular Formula | C22H39O3P | Melting Point | N/A | |
| MSDS | N/A | Flash Point | 276.3±30.9 °C | |
Use of BMP-22BMP-22 is an inhibitor of autotaxin. It is selective for autotaxin over the phosphodiesterases NPP6 and NPP7. BMP-22 inhibits autotaxin-mediated production of lysophosphatidic acid (LPA) from lysophosphatidylcholine (LPC) and inhibits LPC-dependent MM1 cell invasion of a human umbilical vein endothelial cell (HUVEC) monolayer. BMP-22 decreases the number of lung metastatic foci in a B16/F10 syngeneic mouse melanoma model of lung metastasis. |
| Name | BMP-22 |
|---|---|
| Synonym | More Synonyms |
| Density | 1.0±0.1 g/cm3 |
|---|---|
| Boiling Point | 533.2±53.0 °C at 760 mmHg |
| Molecular Formula | C22H39O3P |
| Molecular Weight | 382.517 |
| Flash Point | 276.3±30.9 °C |
| Exact Mass | 382.263672 |
| LogP | 7.66 |
| Vapour Pressure | 0.0±1.5 mmHg at 25°C |
| Index of Refraction | 1.507 |
| Phosphonic acid, [(4-pentadecylphenyl)methyl]- |
| BMP-22 |
| (4-Pentadecylbenzyl)phosphonic acid |