1306684-90-1
1306684-90-1 structure
- Name: BMP-22
- Chemical Name: BMP-22
- CAS Number: 1306684-90-1
- Molecular Formula: C22H39O3P
- Molecular Weight: 382.517
- Create Date: 2021-01-08 23:05:34
- Modify Date: 2024-04-09 11:31:53
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BMP-22 is an inhibitor of autotaxin. It is selective for autotaxin over the phosphodiesterases NPP6 and NPP7. BMP-22 inhibits autotaxin-mediated production of lysophosphatidic acid (LPA) from lysophosphatidylcholine (LPC) and inhibits LPC-dependent MM1 cell invasion of a human umbilical vein endothelial cell (HUVEC) monolayer. BMP-22 decreases the number of lung metastatic foci in a B16/F10 syngeneic mouse melanoma model of lung metastasis.
| Name | BMP-22 |
|---|---|
| Synonyms |
Phosphonic acid, [(4-pentadecylphenyl)methyl]-
BMP-22 (4-Pentadecylbenzyl)phosphonic acid |
| Density | 1.0±0.1 g/cm3 |
|---|---|
| Boiling Point | 533.2±53.0 °C at 760 mmHg |
| Molecular Formula | C22H39O3P |
| Molecular Weight | 382.517 |
| Flash Point | 276.3±30.9 °C |
| Exact Mass | 382.263672 |
| LogP | 7.66 |
| Vapour Pressure | 0.0±1.5 mmHg at 25°C |
| Index of Refraction | 1.507 |