Urolithin D

Modify Date: 2024-01-07 10:18:25

Urolithin D Structure
Urolithin D structure
Common Name Urolithin D
CAS Number 131086-98-1 Molecular Weight 260.20
Density 1.8±0.1 g/cm3 Boiling Point 634.1±55.0 °C at 760 mmHg
Molecular Formula C13H8O6 Melting Point N/A
MSDS N/A Flash Point 253.0±25.0 °C

 Use of Urolithin D


Urolithin D is competitive and reversible antagonist of EphA receptors. Urolithin D exhibits intra-classes selectivity[1].

 Names

Name 3,4,8,9-tetrahydroxybenzo[c]chromen-6-one
Synonym More Synonyms

 Urolithin D Biological Activity

Description Urolithin D is competitive and reversible antagonist of EphA receptors. Urolithin D exhibits intra-classes selectivity[1].
Related Catalog
References

[1]. Giorgio C, et al. The ellagitannin colonic metabolite urolithin D selectively inhibits EphA2 phosphorylation in prostate cancer cells. Mol Nutr Food Res. 2015 Nov;59(11):2155-67.  

 Chemical & Physical Properties

Density 1.8±0.1 g/cm3
Boiling Point 634.1±55.0 °C at 760 mmHg
Molecular Formula C13H8O6
Molecular Weight 260.20
Flash Point 253.0±25.0 °C
Exact Mass 260.032074
PSA 111.13000
LogP 1.07
Vapour Pressure 0.0±1.9 mmHg at 25°C
Index of Refraction 1.801

 Synthetic Route

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Urolithin D Structure

Urolithin D

CAS#:131086-98-1

Literature: AMAZENTIS SA; RINSCH, Christopher, L.; BLANCO-BOSE, William; SCHNEIDER, Bernard; MOUCHIROUD, Laurent; RYU, Dongryeol; ANDREUX, Penelope; AUWERX, Johan Patent: WO2014/4902 A2, 2014 ; Location in patent: Page/Page column 226-227 ;

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Urolithin D Structure

Urolithin D

CAS#:131086-98-1

Literature: Alo, B. I.; Kandil, A.; Patil, P. A.; Sharp, M. J.; Siddiqui, M. A.; et al. Journal of Organic Chemistry, 1991 , vol. 56, # 12 p. 3763 - 3768

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Urolithin D Structure

Urolithin D

CAS#:131086-98-1

Literature: Alo, B. I.; Kandil, A.; Patil, P. A.; Sharp, M. J.; Siddiqui, M. A.; et al. Journal of Organic Chemistry, 1991 , vol. 56, # 12 p. 3763 - 3768

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Urolithin D Structure

Urolithin D

CAS#:131086-98-1

Literature: AMAZENTIS SA; RINSCH, Christopher, L.; BLANCO-BOSE, William; SCHNEIDER, Bernard; MOUCHIROUD, Laurent; RYU, Dongryeol; ANDREUX, Penelope; AUWERX, Johan Patent: WO2014/4902 A2, 2014 ;

~%

Urolithin D Structure

Urolithin D

CAS#:131086-98-1

Literature: AMAZENTIS SA; RINSCH, Christopher, L.; BLANCO-BOSE, William; SCHNEIDER, Bernard; MOUCHIROUD, Laurent; RYU, Dongryeol; ANDREUX, Penelope; AUWERX, Johan Patent: WO2014/4902 A2, 2014 ;

 Synonyms

6H-Dibenzo[b,d]pyran-6-one, 3,4,8,9-tetrahydroxy-
3,4,8,9-Tetrahydroxy-6H-benzo[c]chromen-6-one
3,4,8,9-Tetrahydroxybenzo[c]chromen-6-one
6H-Dibenzo(b,d)pyran-6-one, 3,4,8,9-tetrahydroxy-
urolithin D
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