MDL 27399

Modify Date: 2024-01-31 11:04:03

MDL 27399 structure	Common Name	MDL 27399
	CAS Number	131374-22-6	Molecular Weight	532.58600
	Density	1.239g/cm3	Boiling Point	840.6ºC at 760mmHg
	Molecular Formula	C₂₆H₃₆N₄O₈	Melting Point	N/A
	MSDS	N/A	Flash Point	462.2ºC

Use of MDL 27399

MDL 27399 is an inhibitor of human neutrophil cathepsin G (Ki = 7 μM). MDL 27399 can be used for research of inflammatory diseases[1].

Name	methyl 4-[[(2S)-1-[[(2S)-1-[(2S)-2-[[(2S)-1-methoxy-1-oxo-3-phenylpropan-2-yl]carbamoyl]pyrrolidin-1-yl]-1-oxopropan-2-yl]amino]-1-oxopropan-2-yl]amino]-4-oxobutanoate
Synonym	More Synonyms

Description	MDL 27399 is an inhibitor of human neutrophil cathepsin G (Ki = 7 μM). MDL 27399 can be used for research of inflammatory diseases[1].
Related Catalog	Research Areas >> Inflammation/Immunology Signaling Pathways >> Metabolic Enzyme/Protease >> Cathepsin
References	[1]. N.S. Doherty, et al. Novel inhibitors of polymorphonuclear neutrophil (PMN) elastase and cathepsin G: Evaluation in vitro of their potential for the treatment of inflammatory connective tissue damage. International Journal of Immunopharmacology. Volume 12, Issue 7, 1990, Pages 787-795

Density	1.239g/cm3
Boiling Point	840.6ºC at 760mmHg
Molecular Formula	C₂₆H₃₆N₄O₈
Molecular Weight	532.58600
Flash Point	462.2ºC
Exact Mass	532.25300
PSA	170.68000
LogP	2.29930
Vapour Pressure	1.76E-28mmHg at 25°C
Index of Refraction	1.539

Meo-succ-ala-ala-pro-phe-cooch3

Mdl 27,399