Bis-PEG3-PFP ester

Modify Date: 2024-01-15 07:07:32

Bis-PEG3-PFP ester Structure
Bis-PEG3-PFP ester structure
Common Name Bis-PEG3-PFP ester
CAS Number 1314378-13-6 Molecular Weight 582.342272
Density N/A Boiling Point N/A
Molecular Formula C22H16F10O7 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Bis-PEG3-PFP ester


Bis-PEG3-PFP ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name Bis-PEG3-PFP ester
Synonym More Synonyms

 Bis-PEG3-PFP ester Biological Activity

Description Bis-PEG3-PFP ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

Alkyl/ether

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562.

 Chemical & Physical Properties

Molecular Formula C22H16F10O7
Molecular Weight 582.342272

 Synonyms

BIS-PEG3-PFP ESTER
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