HG6-64-1
Modify Date: 2024-01-17 20:02:56
HG6-64-1 structure
|
Common Name | HG6-64-1 | ||
|---|---|---|---|---|
| CAS Number | 1315329-43-1 | Molecular Weight | 577.640 | |
| Density | 1.3±0.1 g/cm3 | Boiling Point | N/A | |
| Molecular Formula | C32H34F3N5O2 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of HG6-64-1HG6-64-1 is a potent and selective B-Raf inhibitor extracted from patent WO 2011090738 A2, example 9 (XI-1); has a IC50 of 0.09 μM on B-raf V600E transformed Ba/F3 cells. |
| Name | (E)-N-(4-((4-ethylpiperazin-1-yl)methyl)-3-(trifluoromethyl)phenyl)-3-(2-(4-methoxy-1H-pyrrolo[2,3-b]pyridin-5-yl)vinyl)-4-methylbenzamide |
|---|---|
| Synonym | More Synonyms |
| Description | HG6-64-1 is a potent and selective B-Raf inhibitor extracted from patent WO 2011090738 A2, example 9 (XI-1); has a IC50 of 0.09 μM on B-raf V600E transformed Ba/F3 cells. |
|---|---|
| Related Catalog | |
| Target |
B-RafV600E:0.09 μM (IC50, in Ba/F3 cells) |
| References |
[1]. WO 2011090738 A2 |
| Density | 1.3±0.1 g/cm3 |
|---|---|
| Molecular Formula | C32H34F3N5O2 |
| Molecular Weight | 577.640 |
| Exact Mass | 577.266479 |
| PSA | 73.49000 |
| LogP | 6.24 |
| Index of Refraction | 1.651 |
| Storage condition | 2-8℃ |
| N-{4-[(4-Ethyl-1-piperazinyl)methyl]-3-(trifluoromethyl)phenyl}-3-[(E)-2-(4-methoxy-1H-pyrrolo[2,3-b]pyridin-5-yl)vinyl]-4-methylbenzamide |
| Benzamide, N-[4-[(4-ethyl-1-piperazinyl)methyl]-3-(trifluoromethyl)phenyl]-3-[(E)-2-(4-methoxy-1H-pyrrolo[2,3-b]pyridin-5-yl)ethenyl]-4-methyl- |
| hg6-64-1 |