- Shanghai Nianxing Industrial Co., Ltd
- China
- Product Name: HG6-64-1
- Price:
- Purity: 99.0%
- Stocking Period: 10 Day
- Contact: Huang
- DC Chemicals Limited
- China
- Product Name: HG6-64-1
- Price: $800.0/100mg $1600.0/250mg $3200.0/1g
- Purity: 98.0%
- Stocking Period: 3 Day
- Contact: Tony Cao
- ShangHai DC Chemicals Co.,Ltd
- China
- Product Name: HG6-64-1
- Price: ￥Inquiry/1g
- Purity: 98.9%
- Stocking Period: 1 Day
- Contact: Tony Lai
1315329-43-1
1315329-43-1 structure
- Name: HG6-64-1
- Chemical Name: (E)-N-(4-((4-ethylpiperazin-1-yl)methyl)-3-(trifluoromethyl)phenyl)-3-(2-(4-methoxy-1H-pyrrolo[2,3-b]pyridin-5-yl)vinyl)-4-methylbenzamide
- CAS Number: 1315329-43-1
- Molecular Formula: C32H34F3N5O2
- Molecular Weight: 577.640
- Catalog: Research Areas Cancer
- Create Date: 2018-06-18 13:47:21
- Modify Date: 2024-01-17 20:02:56
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HG6-64-1 is a potent and selective B-Raf inhibitor extracted from patent WO 2011090738 A2, example 9 (XI-1); has a IC50 of 0.09 μM on B-raf V600E transformed Ba/F3 cells.
| Name | (E)-N-(4-((4-ethylpiperazin-1-yl)methyl)-3-(trifluoromethyl)phenyl)-3-(2-(4-methoxy-1H-pyrrolo[2,3-b]pyridin-5-yl)vinyl)-4-methylbenzamide |
|---|---|
| Synonyms |
N-{4-[(4-Ethyl-1-piperazinyl)methyl]-3-(trifluoromethyl)phenyl}-3-[(E)-2-(4-methoxy-1H-pyrrolo[2,3-b]pyridin-5-yl)vinyl]-4-methylbenzamide
Benzamide, N-[4-[(4-ethyl-1-piperazinyl)methyl]-3-(trifluoromethyl)phenyl]-3-[(E)-2-(4-methoxy-1H-pyrrolo[2,3-b]pyridin-5-yl)ethenyl]-4-methyl- hg6-64-1 |
| Description | HG6-64-1 is a potent and selective B-Raf inhibitor extracted from patent WO 2011090738 A2, example 9 (XI-1); has a IC50 of 0.09 μM on B-raf V600E transformed Ba/F3 cells. |
|---|---|
| Related Catalog | |
| Target |
B-RafV600E:0.09 μM (IC50, in Ba/F3 cells) |
| References |
[1]. WO 2011090738 A2 |
| Density | 1.3±0.1 g/cm3 |
|---|---|
| Molecular Formula | C32H34F3N5O2 |
| Molecular Weight | 577.640 |
| Exact Mass | 577.266479 |
| PSA | 73.49000 |
| LogP | 6.24 |
| Index of Refraction | 1.651 |
| Storage condition | 2-8℃ |