DOTAP chloride

Modify Date: 2024-01-03 12:33:18

DOTAP chloride Structure
DOTAP chloride structure
Common Name DOTAP chloride
CAS Number 132172-61-3 Molecular Weight 663.08900
Density N/A Boiling Point N/A
Molecular Formula C42H80ClNO4 Melting Point 35-38ºC
MSDS Chinese USA Flash Point N/A

 Use of DOTAP chloride


DOTAP chloride is a useful and effective cationic lipid for transient and stable transfection DNA (plasmids, bacmids) and modified nucleic acids (antisense oligonucleotides) with out the use of helper lipid[1].

 Names

Name 2,3-di(octadec-9-enoyloxy)propyl-trimethylazanium
Synonym More Synonyms

 DOTAP chloride Biological Activity

Description DOTAP chloride is a useful and effective cationic lipid for transient and stable transfection DNA (plasmids, bacmids) and modified nucleic acids (antisense oligonucleotides) with out the use of helper lipid[1].
Related Catalog
Target

IC50: Cationic Lipid[1]

In Vitro liposomes are reorganized by associating with DNA. The transfection efficiency of DOTAP liposomes is mainly influenced by lipid composition and cell type, but not by size or zeta potential[1].
References

[1]. Kim BK, et al. DOTAP/DOPE ratio and cell type determine transfection efficiency with DOTAP-liposomes.Biochim Biophys Acta. 2015 Oct;1848(10 Pt A):1996-2001.

 Chemical & Physical Properties

Melting Point 35-38ºC
Molecular Formula C42H80ClNO4
Molecular Weight 663.08900
Exact Mass 662.60900
PSA 52.60000
LogP 12.22260

 Safety Information

Personal Protective Equipment Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
RIDADR NONH for all modes of transport
WGK Germany 3

 Articles1

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 Synonyms

2,3-dioleyloxypropyltrimethylammonium chloride
1,2-dioleoyl-3-trimethylammonium-propane chloride
1,2-dioleoyl-3-trimethylammonium-propane chloride salt
DOTAP chloride
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