CATPB

Modify Date: 2024-01-04 10:11:04

CATPB Structure
CATPB structure
Common Name CATPB
CAS Number 1322598-09-3 Molecular Weight 399.79
Density 1.3±0.1 g/cm3 Boiling Point 531.4±60.0 °C at 760 mmHg
Molecular Formula C19H17ClF3NO3 Melting Point N/A
MSDS N/A Flash Point 275.2±32.9 °C

 Use of CATPB


CATPB is a potent, selective free fatty acid receptor 2 (FFA2R/GPR43) antagonist[1].

 Names

Name CATPB
Synonym More Synonyms

 CATPB Biological Activity

Description CATPB is a potent, selective free fatty acid receptor 2 (FFA2R/GPR43) antagonist[1].
Related Catalog
Target

FFA2R(GPR43)[1]

In Vitro CATPB inhibits the transient rise in intracellular Ca2+ induced in neutrophils by acetate or Cmp1 (FFAR2 agonist)[1]. CATPB inhibits Cmp1-induced NADPH oxidase activity[1].
References

[1]. Lena Björkman, et al. The Neutrophil Response Induced by an Agonist for Free Fatty Acid Receptor 2 (GPR43) Is Primed by Tumor Necrosis Factor Alpha and by Receptor Uncoupling from the Cytoskeleton but Attenuated by Tissue Recruitment. Mol Cell Biol. 2016 Sep 26;36(20):2583-95.

 Chemical & Physical Properties

Density 1.3±0.1 g/cm3
Boiling Point 531.4±60.0 °C at 760 mmHg
Molecular Formula C19H17ClF3NO3
Molecular Weight 399.79
Flash Point 275.2±32.9 °C
Exact Mass 399.084900
LogP 4.92
Vapour Pressure 0.0±1.5 mmHg at 25°C
Index of Refraction 1.546

 Synonyms

(3S)-3-{(Z)-[2-(3-Chlorophenyl)-1-hydroxyethylidene]amino}-4-[4-(trifluoromethyl)phenyl]butanoic acid
(S)-3-(2-(3-Chlorophenyl)acetamido)-4-(4-(trifluoromethyl)phenyl)butanoic acid
CATPB
Benzenebutanoic acid, β-[[(1Z)-2-(3-chlorophenyl)-1-hydroxyethylidene]amino]-4-(trifluoromethyl)-, (βS)-