Org 12962
Modify Date: 2024-04-03 18:54:45
Org 12962 structure
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Common Name | Org 12962 | ||
|---|---|---|---|---|
| CAS Number | 132834-56-1 | Molecular Weight | 265.66300 | |
| Density | 1.454g/cm3 | Boiling Point | 286.004ºC at 760 mmHg | |
| Molecular Formula | C10H11ClF3N3 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | 126.771ºC | |
Use of Org 12962Org-12962 is a potent, selective and orally active 5-HT2C receptor agonist with a pEC50 value of 7.01. Org-12962 also exhibits high effacy for the 5-HT2A and 5-HT2B receptor with pEC50s of 6.38 and 6.28, respectively[1][3].Org-12962 displays antiaversive effects in a rat model of panic-like anxiety[2]. |
| Name | 1-[6-chloro-5-(trifluoromethyl)pyridin-2-yl]piperazine |
|---|---|
| Synonym | More Synonyms |
| Description | Org-12962 is a potent, selective and orally active 5-HT2C receptor agonist with a pEC50 value of 7.01. Org-12962 also exhibits high effacy for the 5-HT2A and 5-HT2B receptor with pEC50s of 6.38 and 6.28, respectively[1][3].Org-12962 displays antiaversive effects in a rat model of panic-like anxiety[2]. |
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| Related Catalog | |
| Target |
5-HT2C Receptor:7.01 (pEC50) 5-HT2A Receptor:6.38 (pEC50) 5-HT2B Receptor:6.28 (pEC50) |
| In Vivo | Org-12962 (intraperitoneal injection; 0.3-3.2 mg/kg) significantly increases the postinjection frequency thresholds for self-interruption (F3.71=11.40). Org-12962 is dissolved or microsuspended in 0.3% v/v Tween 80 in physiological saline (NaCl 0.9%)[1]. Animal Model: Male Wistar rats[2] Dosage: 0.3 mg/kg, 1 mg/kg, 3.2 mg/kg Administration: Intraperitoneal injection; 0.3-3.2 mg/kg Result: Induced a dose-related antipanic-like effect. |
| References |
| Density | 1.454g/cm3 |
|---|---|
| Boiling Point | 286.004ºC at 760 mmHg |
| Molecular Formula | C10H11ClF3N3 |
| Molecular Weight | 265.66300 |
| Flash Point | 126.771ºC |
| Exact Mass | 265.05900 |
| PSA | 28.16000 |
| LogP | 2.55720 |
| Vapour Pressure | 0.001mmHg at 25°C |
| Index of Refraction | 1.541 |
| HS Code | 2933990090 |
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| Precursor 2 | |
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| DownStream 0 | |
CAS#:110-85-0
CAS#:55304-75-1| HS Code | 2933990090 |
|---|---|
| Summary | 2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
| MFCD00892750 |
- Shanghai Nianxing Industrial Co., Ltd
- China
- Product Name: Org 12962
- Price: Click To Check
- Purity: 98.0%
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- Shanghai Jizhi Biochemical Technology Co., Ltd
- China
- Product Name: Org 12962
- Price: ￥1016.0/250mg ￥2536.0/1g ￥636.0/100mg
- Purity: 95.0%
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- DC Chemicals Limited
- China
- Product Name: Org-12962
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- ShangHai DC Chemicals Co.,Ltd
- China
- Product Name: Org-12962
- Price: ￥Inquiry/1g
- Purity: 98.9%
- Delivery: 1 Day
- Contact: Tony Lai
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- Dayang Chem (Hangzhou) Co., Ltd.
- China
- Product Name: 1-[6-Chloro-5-(trifluoromethyl)-2-pyridinyl]-piperazine
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- Purity: 98.0%
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- Contact: Ms Wang
- Email: enquiry@dycnchem.com
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