Bis-dPEG13-PFP ester

Modify Date: 2024-01-10 17:41:43

Bis-dPEG13-PFP ester Structure
Bis-dPEG13-PFP ester structure
Common Name Bis-dPEG13-PFP ester
CAS Number 1334170-00-1 Molecular Weight 846.657632
Density N/A Boiling Point N/A
Molecular Formula C34H40F10O13 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Bis-dPEG13-PFP ester


Bis-PEG9-PFP ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name Bis-PEG9-PFP ester
Synonym More Synonyms

 Bis-dPEG13-PFP ester Biological Activity

Description Bis-PEG9-PFP ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Molecular Formula C34H40F10O13
Molecular Weight 846.657632

 Synonyms

MFCD20926401