Amino-PEG4-benzyl ester

Modify Date: 2024-01-12 18:59:01

Amino-PEG4-benzyl ester Structure
Amino-PEG4-benzyl ester structure
Common Name Amino-PEG4-benzyl ester
CAS Number 1351397-21-1 Molecular Weight 355.43
Density N/A Boiling Point N/A
Molecular Formula C18H29NO6 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Amino-PEG4-benzyl ester


Amino-PEG4-benzyl ester is a PEG- and Alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name Amino-PEG4-benzyl ester

 Amino-PEG4-benzyl ester Biological Activity

Description Amino-PEG4-benzyl ester is a PEG- and Alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

Alkyl/ether

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. Byung Chul Lee,et al. Synthesis and biological evaluation of RGD peptides with the 99mTc/188Re chelated iminodiacetate core: highly enhanced uptake and excretion kinetics of theranostics against tumor angiogenesis. RSC Advances, 2013, 3, 782.

 Chemical & Physical Properties

Molecular Formula C18H29NO6
Molecular Weight 355.43