5,7,3',4'-Tetrahydroxy-3-Methoxy-8,5'-diprenylflavone

Modify Date: 2024-08-14 11:34:56

5,7,3',4'-Tetrahydroxy-3-Methoxy-8,5'-diprenylflavone Structure
5,7,3',4'-Tetrahydroxy-3-Methoxy-8,5'-diprenylflavone structure
Common Name 5,7,3',4'-Tetrahydroxy-3-Methoxy-8,5'-diprenylflavone
CAS Number 1353676-65-9 Molecular Weight 452.496
Density 1.4±0.1 g/cm3 Boiling Point 694.1±55.0 °C at 760 mmHg
Molecular Formula C26H28O7 Melting Point N/A
MSDS N/A Flash Point 234.7±25.0 °C

 Use of 5,7,3',4'-Tetrahydroxy-3-Methoxy-8,5'-diprenylflavone


5,7,3',4'-Tetrahydroxy-3-methoxy-8,5'-diprenylflavone is a natural product that can be extracted from B. papyrifera. 5,7,3',4'-Tetrahydroxy-3-methoxy-8,5'-diprenylflavone has potent anti-proliferation effects on ER-positive breast cancer cells, with an IC50 value of 4.41 μM for MCF-7 cells. 5,7,3',4'-Tetrahydroxy-3-methoxy-8,5'-diprenylflavone also reduces the tumor growth in the BCAP-37 xenograft[1].

 Names

Name 2-[3,4-Dihydroxy-5-(3-methyl-2-buten-1-yl)phenyl]-5,7-dihydroxy-3-methoxy-8-(3-methyl-2-buten-1-yl)-4H-chromen-4-one
Synonym More Synonyms

  Biological Activity

Description 5,7,3',4'-Tetrahydroxy-3-methoxy-8,5'-diprenylflavone is a natural product that can be extracted from B. papyrifera. 5,7,3',4'-Tetrahydroxy-3-methoxy-8,5'-diprenylflavone has potent anti-proliferation effects on ER-positive breast cancer cells, with an IC50 value of 4.41 μM for MCF-7 cells. 5,7,3',4'-Tetrahydroxy-3-methoxy-8,5'-diprenylflavone also reduces the tumor growth in the BCAP-37 xenograft[1].
Related Catalog
References

[1]. FujiangGuo, et al. Prenylflavone derivatives from Broussonetia papyrifera, inhibit the growth of breast cancer cells in vitro and in vivo. Phytochemistry Letters. Volume 6, Issue 3, August 2013, Pages 331-336.

 Chemical & Physical Properties

Density 1.4±0.1 g/cm3
Boiling Point 694.1±55.0 °C at 760 mmHg
Molecular Formula C26H28O7
Molecular Weight 452.496
Flash Point 234.7±25.0 °C
Exact Mass 452.183502
LogP 6.20
Vapour Pressure 0.0±2.3 mmHg at 25°C
Index of Refraction 1.657
Storage condition 2-8℃

 Safety Information

Hazard Codes Xi

 Synonyms

4H-1-Benzopyran-4-one, 2-[3,4-dihydroxy-5-(3-methyl-2-buten-1-yl)phenyl]-5,7-dihydroxy-3-methoxy-8-(3-methyl-2-buten-1-yl)-
2-[3,4-Dihydroxy-5-(3-methyl-2-buten-1-yl)phenyl]-5,7-dihydroxy-3-methoxy-8-(3-methyl-2-buten-1-yl)-4H-chromen-4-one
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