CYM50179

Modify Date: 2024-01-20 14:50:38

CYM50179 Structure
CYM50179 structure
Common Name CYM50179
CAS Number 1355026-47-9 Molecular Weight 441.93
Density 1.8±0.1 g/cm3 Boiling Point 508.5±50.0 °C at 760 mmHg
Molecular Formula C13H9Br2Cl2NO2 Melting Point N/A
MSDS Chinese USA Flash Point 261.3±30.1 °C
Symbol GHS05 GHS06
GHS05, GHS06
Signal Word Danger

 Use of CYM50179


CYM50179 (compound 22n) is a potent and selective S1P4-R (Sphingosine-1-phosphate4 receptor) agonist with an EC50 of 46 nM[1].

 Names

Name ML-178
Synonym More Synonyms

 CYM50179 Biological Activity

Description CYM50179 (compound 22n) is a potent and selective S1P4-R (Sphingosine-1-phosphate4 receptor) agonist with an EC50 of 46 nM[1].
Related Catalog
Target

S1PR4:46 nM (EC50)

References

[1]. Guerrero M, et al. Discovery, design and synthesis of novel potent and selective sphingosine-1-phosphate 4 receptor (S1P₄-R) agonists. Bioorg Med Chem Lett. 2012 Jan 1;22(1):537-42.

 Chemical & Physical Properties

Density 1.8±0.1 g/cm3
Boiling Point 508.5±50.0 °C at 760 mmHg
Molecular Formula C13H9Br2Cl2NO2
Molecular Weight 441.93
Flash Point 261.3±30.1 °C
Exact Mass 438.837708
LogP 5.62
Vapour Pressure 0.0±1.3 mmHg at 25°C
Index of Refraction 1.620

 Safety Information

Symbol GHS05 GHS06
GHS05, GHS06
Signal Word Danger
Hazard Statements H301-H318-H413
Precautionary Statements P280-P301 + P310-P305 + P351 + P338
RIDADR UN 2811 6.1 / PGIII

 Synonyms

2,6-Dibromo-3-[2-(2,4-dichlorophenoxy)ethoxy]pyridine
Pyridine, 2,6-dibromo-3-[2-(2,4-dichlorophenoxy)ethoxy]-
ML-178