L 696229

Modify Date: 2024-01-05 22:11:27

L 696229 Structure
L 696229 structure
Common Name L 696229
CAS Number 135525-71-2 Molecular Weight 282.33700
Density 1.149g/cm3 Boiling Point 496.5ºC at 760mmHg
Molecular Formula C17H18N2O2 Melting Point N/A
MSDS N/A Flash Point 254.1ºC

 Use of L 696229


L 696229 is a specific inhibitor ofhuman immunodeficiency virus type 1 (HIV-1)reverse transcriptase (RT) activity that possesses antiviral activity[1].

 Names

Name 3-[2-(1,3-benzoxazol-2-yl)ethyl]-5-ethyl-6-methyl-1H-pyridin-2-one
Synonym More Synonyms

 L 696229 Biological Activity

Description L 696229 is a specific inhibitor ofhuman immunodeficiency virus type 1 (HIV-1)reverse transcriptase (RT) activity that possesses antiviral activity[1].
Related Catalog
References

[1]. Goldman ME, et al. L-696,229 specifically inhibits human immunodeficiency virus type 1 reverse transcriptase and possesses antiviral activity in vitro. Antimicrob Agents Chemother. 1992;36(5):1019-1023.  

 Chemical & Physical Properties

Density 1.149g/cm3
Boiling Point 496.5ºC at 760mmHg
Molecular Formula C17H18N2O2
Molecular Weight 282.33700
Flash Point 254.1ºC
Exact Mass 282.13700
PSA 59.15000
LogP 3.58440
Vapour Pressure 5.37E-10mmHg at 25°C
Index of Refraction 1.58

 Synthetic Route

~93%

L 696229 Structure

L 696229

CAS#:135525-71-2

Literature: Saari; Hoffman; Wai; Fisher; Rooney; Smith; Thomas; Goldman; O'Brien; Nunberg; Quintero; Schleif; Emini; Stern; Anderson Journal of Medicinal Chemistry, 1991 , vol. 34, # 9 p. 2922 - 2925

~%

L 696229 Structure

L 696229

CAS#:135525-71-2

Literature: Saari; Hoffman; Wai; Fisher; Rooney; Smith; Thomas; Goldman; O'Brien; Nunberg; Quintero; Schleif; Emini; Stern; Anderson Journal of Medicinal Chemistry, 1991 , vol. 34, # 9 p. 2922 - 2925

~%

L 696229 Structure

L 696229

CAS#:135525-71-2

Literature: Saari; Hoffman; Wai; Fisher; Rooney; Smith; Thomas; Goldman; O'Brien; Nunberg; Quintero; Schleif; Emini; Stern; Anderson Journal of Medicinal Chemistry, 1991 , vol. 34, # 9 p. 2922 - 2925

~%

L 696229 Structure

L 696229

CAS#:135525-71-2

Literature: Hoffman; Smith; Rooney; Fisher; Wai; Thomas; Bamberger; Barnes; Williams; Jones; Olson; O'Brien; Goldman; Nunberg; Quintero; Schleif; Emini; Anderson Journal of Medicinal Chemistry, 1993 , vol. 36, # 8 p. 953 - 966

~%

L 696229 Structure

L 696229

CAS#:135525-71-2

Literature: Saari; Hoffman; Wai; Fisher; Rooney; Smith; Thomas; Goldman; O'Brien; Nunberg; Quintero; Schleif; Emini; Stern; Anderson Journal of Medicinal Chemistry, 1991 , vol. 34, # 9 p. 2922 - 2925

~%

L 696229 Structure

L 696229

CAS#:135525-71-2

Literature: Saari; Hoffman; Wai; Fisher; Rooney; Smith; Thomas; Goldman; O'Brien; Nunberg; Quintero; Schleif; Emini; Stern; Anderson Journal of Medicinal Chemistry, 1991 , vol. 34, # 9 p. 2922 - 2925

 Synonyms

3-[2-(Benzoxazol-2-yl)ethyl]-5-ethyl-6-methyl-pyridin-2(1H)-one
2-pyridinol,3-[2-(2-benzoxazolyl)ethyl]-5-ethyl-6-methyl
3-[2-(benzoxazol-2-yl)ethyl]-5-ethyl-6-methyl-2-(1H)-pyridinone