MK2-IN-28
Modify Date: 2024-04-05 13:32:56
MK2-IN-28 structure
|
Common Name | MK2-IN-28 | ||
|---|---|---|---|---|
| CAS Number | 1355617-50-3 | Molecular Weight | 569.665 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C35H31N5O3 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of MK2-IN-28A potent and selective, non-ATP competitive, allosteric MAPKAPK2/3 (MK2/3) inhibitor with IC50 of 8 nM for MK2, hTNFα EC50 of 0.31 uM; inhibits both MK2 and MK3, and has no or little effect on the other kinases; ameliorates glucose homeostasis by suppressing excessive HGP and enhancing insulin signaling in obese mice. |
| Name | MK2-IN-28 |
|---|
| Description | A potent and selective, non-ATP competitive, allosteric MAPKAPK2/3 (MK2/3) inhibitor with IC50 of 8 nM for MK2, hTNFα EC50 of 0.31 uM; inhibits both MK2 and MK3, and has no or little effect on the other kinases; ameliorates glucose homeostasis by suppressing excessive HGP and enhancing insulin signaling in obese mice. |
|---|---|
| References | References 1. Huang X, et al. Bioorg Med Chem Lett. 2012 Jan 1;22(1):65-70. 2. Ozcan L, et al. Diabetes. 2015 Oct;64(10):3396-405. View Related Products by Target MAPKAPK2 (MK2) |
| Molecular Formula | C35H31N5O3 |
|---|---|
| Molecular Weight | 569.665 |
- Shanghai Nianxing Industrial Co., Ltd
- China
- Product Name: MK2-IN-28
- Price: ￥Inquiry/25mg ￥Inquiry/100mg ￥Inquiry/250mg
- Purity: 98.0%
- Delivery: 10 Day
- Contact: Huang
- Email: sales@echemcloud.com
- DC Chemicals Limited
- China
- Product Name: MK2-IN-28
- Price: $Inquiry/25mg $Inquiry/100mg $Inquiry/250mg
- Purity: 98.0%
- Delivery: 3 Day
- Contact: Tony Cao
- Email: sales@dcchemicals.com
- ShangHai DC Chemicals Co.,Ltd
- China
- Product Name: MK2-IN-28
- Price: ￥Inquiry/1g
- Purity: 98.9%
- Delivery: 1 Day
- Contact: Tony Lai
- Email: order@dcchemicals.com
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