Imidapril-d3 hydrochloride

Modify Date: 2024-01-10 21:18:03

Imidapril-d3 hydrochloride Structure
Imidapril-d3 hydrochloride structure
Common Name Imidapril-d3 hydrochloride
CAS Number 1356017-30-5 Molecular Weight 444.92
Density N/A Boiling Point N/A
Molecular Formula C20H25D3ClN3O6 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Imidapril-d3 hydrochloride


Imidapril-d3 hydrochloride (TA-6366-d3) is the deuterium labeled Imidapril hydrochloride. Imidapril hydrochloride (TA-6366) is the hydrochloride salt of Imidapril, an angiotensin-converting enzyme (ACE) inhibitor with antihypertensive activity[1][2].

 Names

Name Imidapril-d3 hydrochloride

 Imidapril-d3 hydrochloride Biological Activity

Description Imidapril-d3 hydrochloride (TA-6366-d3) is the deuterium labeled Imidapril hydrochloride. Imidapril hydrochloride (TA-6366) is the hydrochloride salt of Imidapril, an angiotensin-converting enzyme (ACE) inhibitor with antihypertensive activity[1][2].
Related Catalog
In Vitro Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.

[2]. Moriya T, et al. Enhancement of swallowing motor activity by the ACE inhibitor imidapril in an arterially perfused rat preparation. Eur J Pharmacol. 2019;861:172601.

 Chemical & Physical Properties

Molecular Formula C20H25D3ClN3O6
Molecular Weight 444.92
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