Vafidemstat

Modify Date: 2024-01-09 22:08:54

Vafidemstat Structure
Vafidemstat structure
Common Name Vafidemstat
CAS Number 1357362-02-7 Molecular Weight 336.39
Density N/A Boiling Point N/A
Molecular Formula C19H20N4O2 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Vafidemstat


Vafidemstat is a dual lysine-specific histone demethylase (LSD1)/MAO-B inhibitor.

 Names

Name Vafidemstat

 Vafidemstat Biological Activity

Description Vafidemstat is a dual lysine-specific histone demethylase (LSD1)/MAO-B inhibitor.
Related Catalog
Target

LSD1/MAO-B[1]

In Vitro Vafidemstat (ORY-2001), a dual LSD1/MAO-B inhibitor, is a novel epigenetic agent for the treatment of neurodegenerative diseases. LSD1 is a protein that participates in transcription regulation complexes; its modulation can be used to tweak transcriptional imbalances in neurodegenerative disease and redress neuroinflammation and cognitive deficit[1]. Vafidemstat (ORY-2001) can be used in the treatment of Alzheimer's disease[2].
References

[1]. ORYZON presents data on the Phase I trial with ORY-2001 at the 13th International Conference on Alzheimer’s and Parkinson’s diseases

[2]. ORYZON Reports Financial Results and Corporate Update for the 1st Half Ended June 30, 2018.

 Chemical & Physical Properties

Molecular Formula C19H20N4O2
Molecular Weight 336.39