ALLM
ALLM structure
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Common Name | ALLM | ||
|---|---|---|---|---|
| CAS Number | 136632-32-1 | Molecular Weight | 401.564 | |
| Density | 1.1±0.1 g/cm3 | Boiling Point | 676.5±55.0 °C at 760 mmHg | |
| Molecular Formula | C19H35N3O4S | Melting Point | N/A | |
| MSDS | USA | Flash Point | 362.9±31.5 °C | |
Use of ALLMA potent, cell-permeable calpain inhibitor with Ki of 0.6 and 100 nM for calpain L and calpain B, respectively; inhibits the activities of Ca(2+)-dependent neutral proteases as well as lysosomal proteases, including cathepsin L, cathepsin B, and cathepsin D; induce apoptosis in rat pituitary tumor cells by specific caspase activation. |
| Name | N-Acetylleucyl-N-[4-(methylsulfanyl)-1-oxo-2-butanyl]leucinamide |
|---|---|
| Synonym | More Synonyms |
| Density | 1.1±0.1 g/cm3 |
|---|---|
| Boiling Point | 676.5±55.0 °C at 760 mmHg |
| Molecular Formula | C19H35N3O4S |
| Molecular Weight | 401.564 |
| Flash Point | 362.9±31.5 °C |
| Exact Mass | 401.234833 |
| LogP | 2.64 |
| Vapour Pressure | 0.0±2.1 mmHg at 25°C |
| Index of Refraction | 1.496 |
| Storage condition | 20°C |
| Personal Protective Equipment | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
|---|---|
| Safety Phrases | S22;S24/25 |
| RIDADR | NONH for all modes of transport |
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Compartmentalization of the chick cerebellar cortex based on the link between the striped expression pattern of aldolase C and the topographic olivocerebellar projection.
J. Comp. Neurol. 523 , 1886-912, (2015) The avian cerebellum is organized into multiple longitudinal stripes defined by expression profiles of aldolase C (zebrin II) in Purkinje cells. The relationship between the aldolase C striped pattern... |
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Targeting microparticle biogenesis: a novel approach to the circumvention of cancer multidrug resistance.
Curr. Cancer Drug Targets 15 , 205-14, (2015) Microparticles (MPs) are released from most eukaryotic cells after the vesiculation of the plasma membrane and serve as vectors of long and short-range signaling. MPs derived from multidrug resistant ... |
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Increased μ-Calpain Activity in Blasts of Common B-Precursor Childhood Acute Lymphoblastic Leukemia Correlates with Their Lower Susceptibility to Apoptosis.
PLoS ONE 10 , e0136615, (2015) Childhood acute lymphoblastic leukemia (ALL) blasts are characterized by inhibited apoptosis promoting fast disease progress. It is known that in chronic lymphocytic and acute myeloid leukemias the re... |
| N-Acetylleucyl-N-[4-(methylsulfanyl)-1-oxobutan-2-yl]leucinamide |
| Leucinamide, N-acetylleucyl-N-[1-formyl-3-(methylthio)propyl]- |
| N-Acetylleucyl-N-[4-(methylsulfanyl)-1-oxo-2-butanyl]leucinamide |
| MFCD00065506 |