136632-32-1
136632-32-1 structure
- Name: ALLM
- Chemical Name: N-Acetylleucyl-N-[4-(methylsulfanyl)-1-oxo-2-butanyl]leucinamide
- CAS Number: 136632-32-1
- Molecular Formula: C19H35N3O4S
- Molecular Weight: 401.564
- Create Date: 2018-04-16 19:45:48
- Modify Date: 2024-01-04 19:22:04
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A potent, cell-permeable calpain inhibitor with Ki of 0.6 and 100 nM for calpain L and calpain B, respectively; inhibits the activities of Ca(2+)-dependent neutral proteases as well as lysosomal proteases, including cathepsin L, cathepsin B, and cathepsin D; induce apoptosis in rat pituitary tumor cells by specific caspase activation.
| Name | N-Acetylleucyl-N-[4-(methylsulfanyl)-1-oxo-2-butanyl]leucinamide |
|---|---|
| Synonyms |
N-Acetylleucyl-N-[4-(methylsulfanyl)-1-oxobutan-2-yl]leucinamide
Leucinamide, N-acetylleucyl-N-[1-formyl-3-(methylthio)propyl]- N-Acetylleucyl-N-[4-(methylsulfanyl)-1-oxo-2-butanyl]leucinamide MFCD00065506 |
| Density | 1.1±0.1 g/cm3 |
|---|---|
| Boiling Point | 676.5±55.0 °C at 760 mmHg |
| Molecular Formula | C19H35N3O4S |
| Molecular Weight | 401.564 |
| Flash Point | 362.9±31.5 °C |
| Exact Mass | 401.234833 |
| LogP | 2.64 |
| Vapour Pressure | 0.0±2.1 mmHg at 25°C |
| Index of Refraction | 1.496 |
| Storage condition | 20°C |
| Personal Protective Equipment | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
|---|---|
| Safety Phrases | S22;S24/25 |
| RIDADR | NONH for all modes of transport |