BChE-IN-12

Modify Date: 2024-04-02 21:05:04

BChE-IN-12 Structure
BChE-IN-12 structure
Common Name BChE-IN-12
CAS Number 136966-86-4 Molecular Weight 482.57
Density N/A Boiling Point N/A
Molecular Formula C31H30O5 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of BChE-IN-12


BChE-IN-12 (compound 12) is a potent butyrylcholinesterase (BChE) non-competitive inhibitor with an IC50 value of 2.3 μM. BChE-IN-12 can be isolated from Bletilla striata. BChE-IN-12 can be used for the research of Alzheimer's disease (AD)[1].

 Names

Name BChE-IN-12

 BChE-IN-12 Biological Activity

Description BChE-IN-12 (compound 12) is a potent butyrylcholinesterase (BChE) non-competitive inhibitor with an IC50 value of 2.3 μM. BChE-IN-12 can be isolated from Bletilla striata. BChE-IN-12 can be used for the research of Alzheimer's disease (AD)[1].
Related Catalog
Target

BChE:2.3 μM (IC50)

References

[1]. Liu Y, et al. Biological evaluation, molecular modeling and dynamics simulation of phenanthrenes isolated from Bletilla striata as butyrylcholinesterase inhibitors. Sci Rep. 2022 Aug 11;12(1):13649.

 Chemical & Physical Properties

Molecular Formula C31H30O5
Molecular Weight 482.57