Amprolium Hydrochloride

Modify Date: 2024-01-02 17:13:30

Amprolium Hydrochloride Structure
Amprolium Hydrochloride structure
Common Name Amprolium Hydrochloride
CAS Number 137-88-2 Molecular Weight 315.241
Density N/A Boiling Point N/A
Molecular Formula C14H20Cl2N4 Melting Point 241 °C
MSDS Chinese USA Flash Point N/A

 Use of Amprolium Hydrochloride


Amprolium hydrochloride is a coccidiostat used in poultry, is a thiamine analogue and blocks the thiamine transporter of Eimeria species by blocking thiamine uptake it prevents carbohydrate synthesis.

 Names

Name 1-([4-Amino-2-propyl-5-pyrimidinyl]methyl)-2-methylpyridinium chloride
Synonym More Synonyms

 Amprolium Hydrochloride Biological Activity

Description Amprolium hydrochloride is a coccidiostat used in poultry, is a thiamine analogue and blocks the thiamine transporter of Eimeria species by blocking thiamine uptake it prevents carbohydrate synthesis.
Related Catalog

 Chemical & Physical Properties

Melting Point 241 °C
Molecular Formula C14H20Cl2N4
Molecular Weight 315.241
Exact Mass 314.106506
PSA 55.68000
LogP 0.04270

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
TJ7565000
CHEMICAL NAME :
2-Picolinium, 1-((4-amino-2-propyl-5-pyrimidinyl)methyl)-, chloride, monohydrochloride
CAS REGISTRY NUMBER :
137-88-2
LAST UPDATED :
199410
DATA ITEMS CITED :
1
MOLECULAR FORMULA :
C14-H19-N4.Cl.Cl-H
MOLECULAR WEIGHT :
315.28

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

MUTATION DATA

TYPE OF TEST :
Mutation in microorganisms
TEST SYSTEM :
Bacteria - Salmonella typhimurium
DOSE/DURATION :
10 mg/plate
REFERENCE :
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 77,21,1980

 Safety Information

Personal Protective Equipment Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Hazard Codes Xn: Harmful;
Risk Phrases R20/21/22
Safety Phrases S22-S24/25
RIDADR NONH for all modes of transport
WGK Germany 3
RTECS TJ7565000
HS Code 29335995

 Articles26

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Veterinary drug residues in domestic and imported foods of animal origin in the Republic of Korea.

Food. Addit. Contam. Part. B. Surveill. 8 , 106-12, (2015)

The Korean National Residue Programme comprises three different approaches for evaluating domestic and imported foods of animal origin: monitoring, surveillance/enforcement and an exploratory test pro...

Ethanol promotes thiamine deficiency-induced neuronal death: involvement of double-stranded RNA-activated protein kinase.

Alcohol. Clin. Exp. Res. 33(6) , 1097-103, (2009)

Heavy alcohol consumption causes cerebellar degeneration, and the underlying mechanism is unclear. Chronic alcoholism is usually associated with thiamine deficiency (TD) which is known to induce selec...

Determination of amprolium in feed by a liquid chromatography-mass spectrometry method.

J. Pharm. Biomed. Anal. 48(5) , 1457-61, (2008)

As a consequence of the finding of veterinarian drugs in food European Community banned several compounds like coccidiostats as amprolium (APL). This antibiotic has been used as a preventive and clini...

 Synonyms

mepyrium
AmproliumHclUsp27
MFCD00078831
thiacoccid
1-[(4-Amino-2-propyl-5-pyrimidinyl)methyl]-2-methylpyridinium Chloride Hydrochloride
AMPROLIUM HYDROCHLORIDE VETRANAL,250
AMPROLIUM HYDROCHLORIDE
Thiacoccide
Amprolium HCl
EINECS 205-307-5
Amprolium (hydrochloride)
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