Cavosonstat

Modify Date: 2024-01-11 18:30:49

Cavosonstat Structure
Cavosonstat structure
Common Name Cavosonstat
CAS Number 1371587-51-7 Molecular Weight 299.708
Density 1.5±0.1 g/cm3 Boiling Point 527.5±50.0 °C at 760 mmHg
Molecular Formula C16H10ClNO3 Melting Point N/A
MSDS N/A Flash Point 272.8±30.1 °C

 Use of Cavosonstat


Cavosonstat (N91115) is an orally active S-nitrosoglutathione reductase (GSNOR) inhibitor. Cavosonstat is a CFTR stabilizer, and can be used for cystic fibrosis research[1].

 Names

Name Cavosonstat
Synonym More Synonyms

 Cavosonstat Biological Activity

Description Cavosonstat (N91115) is an orally active S-nitrosoglutathione reductase (GSNOR) inhibitor. Cavosonstat is a CFTR stabilizer, and can be used for cystic fibrosis research[1].
Related Catalog
In Vitro Cavosonstat (N91115), a CFTR modulator, promotes cystic fibrosis transmembrane conductance regulator (CFTR) maturation and plasma membrane stability, with a mechanism of action complementary to CFTR correctors and potentiators[1].
References

[1]. Scott H Donaldson, et al. Pharmacokinetics and safety of cavosonstat (N91115) in healthy and cystic fibrosis adults homozygous for F508DEL-CFTR. J Cyst Fibros. 2017 May;16(3):371-379.

 Chemical & Physical Properties

Density 1.5±0.1 g/cm3
Boiling Point 527.5±50.0 °C at 760 mmHg
Molecular Formula C16H10ClNO3
Molecular Weight 299.708
Flash Point 272.8±30.1 °C
Exact Mass 299.034912
LogP 4.28
Vapour Pressure 0.0±1.5 mmHg at 25°C
Index of Refraction 1.715

 Synonyms

3-Chloro-4-(6-hydroxy-2-quinolinyl)benzoic acid
O2Z8Q22ZE4
UNII:O2Z8Q22ZE4
Cavosonstat
10452
N91115
Benzoic acid, 3-chloro-4-(6-hydroxy-2-quinolinyl)-
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