Dehydroeffusol

Modify Date: 2024-01-06 19:49:19

Dehydroeffusol Structure
Dehydroeffusol structure
Common Name Dehydroeffusol
CAS Number 137319-34-7 Molecular Weight 250.29200
Density N/A Boiling Point N/A
Molecular Formula C17H14O2 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Dehydroeffusol


Dehydroeffusol is a phenanthrene from medicinal herb Juncus effuses. Dehydroeffusol inhibits gastric cancer cell growth and tumorigenicity by selectively inducing tumor-suppressive endoplasmic reticulum stress and a moderate apoptosis. It shows very low toxicity[1][2].

 Names

Name Dehydro Effusol
Synonym More Synonyms

 Dehydroeffusol Biological Activity

Description Dehydroeffusol is a phenanthrene from medicinal herb Juncus effuses. Dehydroeffusol inhibits gastric cancer cell growth and tumorigenicity by selectively inducing tumor-suppressive endoplasmic reticulum stress and a moderate apoptosis. It shows very low toxicity[1][2].
Related Catalog
In Vitro Dehydroeffusol suppresses the expression of vasculogenic mimicry key gene VE-cadherin[2]. Dehydroeffusol decreases the MMP2 expression and activity in gastric cancer cells[2].
References

[1]. Zhang B, et al. Dehydroeffusol inhibits gastric cancer cell growth and tumorigenicity by selectively inducing tumor-suppressive endoplasmic reticulum stress and a moderate apoptosis. Biochem Pharmacol. 2016 Mar 15;104:8-18.

[2]. Liu W, et al. Dehydroeffusol effectively inhibits human gastric cancer cell-mediated vasculogenic mimicry with low toxicity. Toxicol Appl Pharmacol. 2015 Sep 1;287(2):98-110.

 Chemical & Physical Properties

Molecular Formula C17H14O2
Molecular Weight 250.29200
Exact Mass 250.09900
PSA 40.46000
LogP 4.35560

 Synonyms

5-ethenyl-1-methylphenanthrene-2,7-diol
5-Ethenyl-1-methyl-2,7-phenanthrenediol
Dehydroeffusol