Mal-peg2-t-butyl ester

Modify Date: 2024-01-10 12:53:48

Mal-peg2-t-butyl ester Structure
Mal-peg2-t-butyl ester structure
Common Name Mal-peg2-t-butyl ester
CAS Number 1374666-31-5 Molecular Weight 313.35
Density N/A Boiling Point N/A
Molecular Formula C15H23NO6 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Mal-peg2-t-butyl ester


Mal-PEG2-C2-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name Mal-PEG2-C2-Boc
Synonym More Synonyms

 Mal-peg2-t-butyl ester Biological Activity

Description Mal-PEG2-C2-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Molecular Formula C15H23NO6
Molecular Weight 313.35

 Synonyms

MFCD23726621