EZH2-IN-3
Modify Date: 2024-01-02 11:15:14
EZH2-IN-3 structure
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Common Name | EZH2-IN-3 | ||
|---|---|---|---|---|
| CAS Number | 1377997-28-8 | Molecular Weight | 489.996 | |
| Density | 1.3±0.1 g/cm3 | Boiling Point | 666.4±55.0 °C at 760 mmHg | |
| Molecular Formula | C27H28ClN5O2 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | 356.8±31.5 °C | |
Use of EZH2-IN-3EZH2-IN-3 is a highly selective small molecule inhibitor of EZH2 and EZH1 with IC50 of 21/197/213 nM for wt EZH2/EZH2 Y641N/wt EZH1 respectively; suppresses global histone H3-lysine 27 methylation and cause selective proliferation defects. |
| Name | 3-Chloro-4-[2-cyano-3-(4-pyridazinyl)phenoxy]-N-(2,2,6,6-tetramethyl-4-piperidinyl)benzamide |
|---|---|
| Synonym | More Synonyms |
| Description | EZH2-IN-3 is a highly selective small molecule inhibitor of EZH2 and EZH1 with IC50 of 21/197/213 nM for wt EZH2/EZH2 Y641N/wt EZH1 respectively; suppresses global histone H3-lysine 27 methylation and cause selective proliferation defects. |
|---|---|
| References | References 1. Garapaty-Rao S, et al. Chem Biol. 2013 Nov 21;20(11):1329-39. View Related Products by Target Histone Methyltransferase (HMTase) |
| Density | 1.3±0.1 g/cm3 |
|---|---|
| Boiling Point | 666.4±55.0 °C at 760 mmHg |
| Molecular Formula | C27H28ClN5O2 |
| Molecular Weight | 489.996 |
| Flash Point | 356.8±31.5 °C |
| Exact Mass | 489.193146 |
| LogP | 4.63 |
| Vapour Pressure | 0.0±2.0 mmHg at 25°C |
| Index of Refraction | 1.631 |
| 3-Chloro-4-[2-cyano-3-(4-pyridazinyl)phenoxy]-N-(2,2,6,6-tetramethyl-4-piperidinyl)benzamide |
| Benzamide, 3-chloro-4-[2-cyano-3-(4-pyridazinyl)phenoxy]-N-(2,2,6,6-tetramethyl-4-piperidinyl)- |
- Shanghai Nianxing Industrial Co., Ltd
- China
- Product Name: EZH2-IN-3
- Price: Negotiable
- Purity: 98.0%
- Delivery: 10 Day
- Contact: Huang
- Email: sales@echemcloud.com
- DC Chemicals Limited
- China
- Product Name: EZH2-IN-3
- Price: $Inquiry/100mg $Inquiry/250mg $Inquiry/1g
- Purity: 98.0%
- Delivery: 3 Day
- Contact: Tony Cao
- Email: sales@dcchemicals.com
- ShangHai DC Chemicals Co.,Ltd
- China
- Product Name: EZH2-IN-3
- Price: ￥Inquiry/1g
- Purity: 98.9%
- Delivery: 1 Day
- Contact: Tony Lai
- Email: order@dcchemicals.com
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