1403258-69-4
1403258-69-4 structure
- Name: EZH2-IN-5
- Chemical Name: EZH2-IN-5
- CAS Number: 1403258-69-4
- Molecular Formula: C26H37BrN4O2
- Molecular Weight: 517.50
- Catalog: Signaling Pathways Epigenetics Histone Methyltransferase
- Create Date: 2021-09-12 13:14:30
- Modify Date: 2024-01-09 15:42:17
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EZH2-IN-5 is a potent EZH2 inhibitor with IC50 values of 1.52 nM and 4.07 nM for wild-type and mutant Tyr641 EZH2, respectively[1].
| Name | EZH2-IN-5 |
|---|
| Description | EZH2-IN-5 is a potent EZH2 inhibitor with IC50 values of 1.52 nM and 4.07 nM for wild-type and mutant Tyr641 EZH2, respectively[1]. |
|---|---|
| Related Catalog | |
| Target |
EZH2 WT:1.52 nM (IC50) EZH2 Y641F mutant type:4.07 nM (IC50) |
| In Vitro | EZH2-IN-5 (compound 276) inhibits cell growth of WSUDLCL2 cell lines with an IC50 of 187.28 nM[1]. |
| References |
[1]. Richard Chesworth, et al. Substituted benzene compounds. WO2012142513A1 |
| Molecular Formula | C26H37BrN4O2 |
|---|---|
| Molecular Weight | 517.50 |