Cyclo [Arg-Gly-Asp-D-Phe-Val]

Modify Date: 2024-01-06 13:54:41

Cyclo [Arg-Gly-Asp-D-Phe-Val] structure	Common Name	Cyclo [Arg-Gly-Asp-D-Phe-Val]
	CAS Number	137813-35-5	Molecular Weight	574.62900
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₆H₃₈N₈O₇	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of Cyclo [Arg-Gly-Asp-D-Phe-Val]

Cyclo(Arg-Gly-Asp-D-Phe-Val) is an integrin αvβ3 inhibitor. Cyclo(Arg-Gly-Asp-D-Phe-Val) has antitumor activity. Cyclo(Arg-Gly-Asp-D-Phe-Val) can be used for the research of acute myeloid leukemia[1].

Name	cyclo(arg-gly-asp-d-phe-val)
Synonym	More Synonyms

Description	Cyclo(Arg-Gly-Asp-D-Phe-Val) is an integrin αvβ3 inhibitor. Cyclo(Arg-Gly-Asp-D-Phe-Val) has antitumor activity. Cyclo(Arg-Gly-Asp-D-Phe-Val) can be used for the research of acute myeloid leukemia[1].
Related Catalog	Signaling Pathways >> Apoptosis >> Apoptosis Research Areas >> Cancer Signaling Pathways >> Cytoskeleton >> Integrin
Target	αvβ3[1]
In Vitro	Cyclo(Arg-Gly-Asp-d-Phe-Val) (c(RGDfV)) (35 nM, 4-24 h) disruptes the adhesion and migration between the tumor cells and the matrix, induces the leukemia cells to leave the protective microenvironment and increases their sensitivity to cell cycle-dependent agents[1]. Cell Cycle Analysis[1] Cell Line: MV4–11 cells Concentration: 35 nM Incubation Time: 24 h Result: Affected the leukemia cell cycle, decreased the G0/G1 phase of leukemia cells in the 3D and 2D culture systems and increased the S phase of leukemia cells in the 3D and 2D culture systems. Apoptosis Analysis[1] Cell Line: MV4–11 cells Concentration: 35 nM Incubation Time: 24 h Result: Increased the apoptosis rates.

Molecular Formula	C₂₆H₃₈N₈O₇
Molecular Weight	574.62900
Exact Mass	574.28600
PSA	244.70000
LogP	0.52700

RGDFV PEPTIDE,CYCLIC

Cyclo(Arg-Gly-Asp-D-Phe-Val)

Shanghai Nianxing Industrial Co., Ltd
China
Product Name: Cyclo [Arg-Gly-Asp-D-Phe-Val]
Price: Click To Check
Purity: 98.0%
Delivery: 10 Day
Contact: Yang
Email: sales@echemcloud.com

Taiwan Oyi peptide Co. Ltd
China
Product Name: Cyclo [Arg-Gly-Asp-D-Phe-Val]
Price: $Inquiry/1mg $Inquiry/100kg
Purity: 98.0%
Delivery: 1 Day
Contact: Vinnie
Email: Jamie@api-made.com

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