Puwainaphycin F

Modify Date: 2024-01-11 16:54:02

Puwainaphycin F Structure
Puwainaphycin F structure
Common Name Puwainaphycin F
CAS Number 1379577-47-5 Molecular Weight 1146.34
Density N/A Boiling Point N/A
Molecular Formula C53H87N13O15 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Puwainaphycin F


Puwainaphycin F, a cyanobacterial cyclic lipopeptide, is a moderate cytotoxin isolated from the soil cyanobacterium Cylindrospermum alatosporum C24/89. Puwainaphycin F causes necrotic cell death to mammalian cells via cell membrane permeabilization and subsequent unusual actin relocalization[1].

 Names

Name Puwainaphycin F

 Puwainaphycin F Biological Activity

Description Puwainaphycin F, a cyanobacterial cyclic lipopeptide, is a moderate cytotoxin isolated from the soil cyanobacterium Cylindrospermum alatosporum C24/89. Puwainaphycin F causes necrotic cell death to mammalian cells via cell membrane permeabilization and subsequent unusual actin relocalization[1].
Related Catalog
In Vitro Puwainaphycin F has an IC50 of 2.19 μM in HeLa cells[1].
References

[1]. Pavel Hrouzek , et al. The cyanobacterial cyclic lipopeptides puwainaphycins F/G are inducing necrosis via cell membrane permeabilization and subsequent unusual actin relocalization. Chem Res Toxicol. 2012 Jun 18;25(6):1203-11.

 Chemical & Physical Properties

Molecular Formula C53H87N13O15
Molecular Weight 1146.34
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