Protizinic acid
Modify Date: 2024-01-13 23:09:14
Protizinic acid structure
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Common Name | Protizinic acid | ||
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| CAS Number | 13799-03-6 | Molecular Weight | 315.39 | |
| Density | 1.285g/cm3 | Boiling Point | 524.6ºC at 760mmHg | |
| Molecular Formula | C17H17NO3S | Melting Point | N/A | |
| MSDS | N/A | Flash Point | 271.1ºC | |
Use of Protizinic acidProtizinic acid is an orally active non-steroidal antiinflammatory agent with antiinflammatory and antipyretic activity. Protizinic acid inhibits phospholipase A2 (PLA2) activity, and the IC50 value is 210 μM[1][2]. |
| Name | protizinic acid |
|---|---|
| Synonym | More Synonyms |
| Description | Protizinic acid is an orally active non-steroidal antiinflammatory agent with antiinflammatory and antipyretic activity. Protizinic acid inhibits phospholipase A2 (PLA2) activity, and the IC50 value is 210 μM[1][2]. |
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| Related Catalog | |
| Target |
PLA2:210 μM (IC50) |
| In Vitro | Protizinic acid not only inhibits the in vitro generation of leukokinin but also antagonizes to it on the receptor site of leukokinin[1]. |
| In Vivo | In vivo leukokinin (LK) generation system using feline acute ischemia model, When 3 mg/kg Protizinic acid is injected twice intravenously to cats with acute cardiac ischemia, increased blood acid protease activity is inhibited and significant inhibitory action on the decrease of leukokininogen, the precursor of leukokinin, is observed[1]. Oral administration of 30 mg/kg of Protizinic acid significantly inhibits arachidonic acid-induced erythema in guinea pigs[2]. |
| References |
| Density | 1.285g/cm3 |
|---|---|
| Boiling Point | 524.6ºC at 760mmHg |
| Molecular Formula | C17H17NO3S |
| Molecular Weight | 315.39 |
| Flash Point | 271.1ºC |
| Exact Mass | 315.09300 |
| PSA | 75.07000 |
| LogP | 4.18080 |
| Vapour Pressure | 7.83E-12mmHg at 25°C |
| Index of Refraction | 1.636 |
| HS Code | 2934300000 |
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| HS Code | 2934300000 |
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| Summary | 2934300000. other compounds containing in the structure a phenothiazine ring-system (whether or not hydrogenated), not further fused. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
| Protizinic |
| Pirocrid |