Tetrazine-Acid

Modify Date: 2024-04-03 11:24:30

Tetrazine-Acid Structure
Tetrazine-Acid structure
Common Name Tetrazine-Acid
CAS Number 1380500-92-4 Molecular Weight 216.20
Density N/A Boiling Point N/A
Molecular Formula C10H8N4O2 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Tetrazine-Acid


Tetrazine-Ph-acid is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name Tetrazine-Ph-acid

 Tetrazine-Acid Biological Activity

Description Tetrazine-Ph-acid is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

Alkyl-Chain

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Molecular Formula C10H8N4O2
Molecular Weight 216.20