Z-VRPR-FMK(Z-Val-Arg-Pro-DL-Arg-FMK
Modify Date: 2024-01-10 16:47:46
Z-VRPR-FMK(Z-Val-Arg-Pro-DL-Arg-FMK structure
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Common Name | Z-VRPR-FMK(Z-Val-Arg-Pro-DL-Arg-FMK | ||
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| CAS Number | 1381885-28-4 | Molecular Weight | 1666.158 | |
| Density | 1.2±0.1 g/cm3 | Boiling Point | 1659.8±65.0 °C at 760 mmHg | |
| Molecular Formula | C84H140N14O18S | Melting Point | N/A | |
| MSDS | N/A | Flash Point | 957.6±34.3 °C | |
Use of Z-VRPR-FMK(Z-Val-Arg-Pro-DL-Arg-FMKZ-VRPR-FMK is an irreversible MALT1 protein inhibitor. Z-VRPR-FMK inhibits the growth and invasion of diffuse large B-cell lymphoma by inhibiting MALT1-induced NF-κB activation and MMP expression[1]. |
| Name | S-[2,3-Bis(palmitoyloxy)propyl]-L-cysteinylglycyl-L-α-aspartyl-L-prolyl-L-lysyl-L-histidyl-L-prolyl-L-lysyl-L-seryl-L-phenylalanine |
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| Synonym | More Synonyms |
| Description | Z-VRPR-FMK is an irreversible MALT1 protein inhibitor. Z-VRPR-FMK inhibits the growth and invasion of diffuse large B-cell lymphoma by inhibiting MALT1-induced NF-κB activation and MMP expression[1]. |
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| Related Catalog | |
| In Vitro | Z-VRPR-FMK(50 μM, 24 h)可以有效降低 HBL-1 细胞核 c-REL 水平，抑制了 NF-κB 的信号传导[2]。 Z-VRPR-FMK(50 μM, 48 h)对 ABC-DLBCL 细胞系 HBL-1, TMD8, OCI-Ly3 和 OCI-Ly10 具有一定的抑制增殖作用[2]。 |
| References |
| Density | 1.2±0.1 g/cm3 |
|---|---|
| Boiling Point | 1659.8±65.0 °C at 760 mmHg |
| Molecular Formula | C84H140N14O18S |
| Molecular Weight | 1666.158 |
| Flash Point | 957.6±34.3 °C |
| Exact Mass | 1665.019043 |
| LogP | 15.83 |
| Vapour Pressure | 0.0±0.3 mmHg at 25°C |
| Index of Refraction | 1.553 |
| L-Phenylalanine, S-[2,3-bis[(1-oxohexadecyl)oxy]propyl]-L-cysteinylglycyl-L-α-aspartyl-L-prolyl-L-lysyl-L-histidyl-L-prolyl-L-lysyl-L-seryl- |
| S-[2,3-Bis(palmitoyloxy)propyl]-L-cysteinylglycyl-L-α-aspartyl-L-prolyl-L-lysyl-L-histidyl-L-prolyl-L-lysyl-L-seryl-L-phenylalanine |