Stearyl glycyrrhetinate

Modify Date: 2024-01-02 10:34:20

Stearyl glycyrrhetinate Structure
Stearyl glycyrrhetinate structure
Common Name Stearyl glycyrrhetinate
CAS Number 13832-70-7 Molecular Weight 723.162
Density 1.0±0.1 g/cm3 Boiling Point 732.5±60.0 °C at 760 mmHg
Molecular Formula C48H82O4 Melting Point 70-77ºC
MSDS N/A Flash Point 198.8±26.4 °C

 Use of Stearyl glycyrrhetinate


Stearyl glycyrrhetinate, a major component in licorice extract, has a MIC against S. aureus strains of more than 256 mg/L. Stearyl glycyrrhetinate has antibacterial effects[1].

 Names

Name octadecyl (2S,4aS,6aR,6aS,6bR,8aR,10S,12aS,14bR)-10-hydroxy-2,4a,6a,6b,9,9,12a-heptamethyl-13-oxo-3,4,5,6,6a,7,8,8a,10,11,12,14b-dodecahydro-1H-picene-2-carboxylate
Synonym More Synonyms

 Stearyl glycyrrhetinate Biological Activity

Description Stearyl glycyrrhetinate, a major component in licorice extract, has a MIC against S. aureus strains of more than 256 mg/L. Stearyl glycyrrhetinate has antibacterial effects[1].
Related Catalog
In Vitro Glycyrrhetinic acid (GRA) and disodium succinoyl glycyrrhetinate (GR-SU) shows strong antibacterial activities compared to the other three agents tested. At a higher concentration (above 2x MIC), GRA and GR-SU shows bactericidal activity, whereas at a concentration of 1x MIC, they showed a bacteriostatic effect[1].
References

[1]. Oyama K, et al. Antibacterial Effects of Glycyrrhetinic Acid and Its Derivatives on Staphylococcus aureus. PLoS One. 2016 Nov 7;11(11):e0165831.

 Chemical & Physical Properties

Density 1.0±0.1 g/cm3
Boiling Point 732.5±60.0 °C at 760 mmHg
Melting Point 70-77ºC
Molecular Formula C48H82O4
Molecular Weight 723.162
Flash Point 198.8±26.4 °C
Exact Mass 722.621338
PSA 63.60000
LogP 16.03
Vapour Pressure 0.0±5.4 mmHg at 25°C
Index of Refraction 1.525

 Safety Information

HS Code 2918990090

 Customs

HS Code 2918990090
Summary 2918990090. other carboxylic acids with additional oxygen function and their anhydrides, halides, peroxides and peroxyacids; their halogenated, sulphonated, nitrated or nitrosated derivatives. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

 Synonyms

Olean-12-en-30-oic acid, 3-hydroxy-11-oxo-, octadecyl ester, (3β,5ξ,18α)-
Stearyl glycyrrhetinate
a-Glycyrrhetinic acid stearyl ester
Octadecyl glycyrrhetinate
Olean-12-en-30-oicacid,3b-hydroxy-11-oxo-,octadecyl ester(8CI)
stearyl glycyrrhizinate
n-Octadecyl glycyrrhetinate
Olean-12-en-30-oic acid, 3-hydroxy-11-oxo-, octadecyl ester, (3β)-
stearyl glycyrrhizate
stearyl glycyrrhetate
Octadecyl (3β)-3-hydroxy-11-oxoolean-12-en-30-oate
CO-Grhetinol
Octadecyl (3β,5ξ,18α)-3-hydroxy-11-oxoolean-12-en-30-oate
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