Hedycoronen A

Modify Date: 2024-01-11 11:32:32

Hedycoronen A Structure
Hedycoronen A structure
Common Name Hedycoronen A
CAS Number 1383441-73-3 Molecular Weight 330.46
Density 1.1±0.1 g/cm3 Boiling Point 458.2±45.0 °C at 760 mmHg
Molecular Formula C21H30O3 Melting Point N/A
MSDS N/A Flash Point 196.6±23.3 °C

 Use of Hedycoronen A


Hedycoronen A has inhibitory activity on the IL-6, IL-12 p40, and TNF-α production in LPS-Stimulated BMDCs, with IC50s of 9.1 μM, 5.6 μM, and 46.0 μM. Hedycoronen A can be isolated from Hedychium coronarium[1].

 Names

Name 5-methoxy-3-((E)-2-((1S,4aS,8aS)-5,5,8a-trimethyl-2-methylenedecahydronaphthalen-1-yl)vinyl)furan-2(5H)-one
Synonym More Synonyms

 Hedycoronen A Biological Activity

Description Hedycoronen A has inhibitory activity on the IL-6, IL-12 p40, and TNF-α production in LPS-Stimulated BMDCs, with IC50s of 9.1 μM, 5.6 μM, and 46.0 μM. Hedycoronen A can be isolated from Hedychium coronarium[1].
Related Catalog
References

[1]. Kiem PV, et al. Labdane-type diterpenoids from the rhizomes of Hedychium coronarium inhibit lipopolysaccharide-stimulated production of pro-inflammatory cytokines in bone marrow-derived dendritic cells. Chem Pharm Bull (Tokyo). 2012;60(2):246-50.  

 Chemical & Physical Properties

Density 1.1±0.1 g/cm3
Boiling Point 458.2±45.0 °C at 760 mmHg
Molecular Formula C21H30O3
Molecular Weight 330.46
Flash Point 196.6±23.3 °C
Exact Mass 330.219482
PSA 35.53000
LogP 4.90
Vapour Pressure 0.0±1.1 mmHg at 25°C
Index of Refraction 1.529

 Safety Information

Hazard Codes Xi

 Synonyms

2(5H)-Furanone, 3-[(E)-2-[(1S,4aS,8aS)-decahydro-5,5,8a-trimethyl-2-methylene-1-naphthalenyl]ethenyl]-5-methoxy-
5-Methoxy-3-{(E)-2-[(1S,4aS,8aS)-5,5,8a-trimethyl-2-methylenedecahydro-1-naphthalenyl]vinyl}-2(5H)-furanone
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