Euphol Acetate

Modify Date: 2024-01-16 05:35:50

Euphol Acetate Structure
Euphol Acetate structure
Common Name Euphol Acetate
CAS Number 13879-04-4 Molecular Weight 468.75
Density N/A Boiling Point N/A
Molecular Formula C32H52O2 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Euphol Acetate


Euphol acetate is a triterpene that can be isolated from Euphorbia broteri. Euphol acetate is an inhibitor of hepatic transport proteins organic anion-transporting polypeptide 1/3 (OATP1B1/3)[1][2].

 Names

Name Euphol Acetate

 Euphol Acetate Biological Activity

Description Euphol acetate is a triterpene that can be isolated from Euphorbia broteri. Euphol acetate is an inhibitor of hepatic transport proteins organic anion-transporting polypeptide 1/3 (OATP1B1/3)[1][2].
Related Catalog
Target

OATP1B1/3[2]

In Vitro Euphol acetate (10μM) suppresses the uptake of the OATP1B substrate sodium fluorescein in OATP1B1 (29.2%)- or 1B3 (40.2%)-transfected CHO cells[2].
References

[1]. DePascual Teresa, et al. Triterpenes from Euphorbia broteri. Phytochemistry. 1987. 26(6): 1767-1776.

[2]. Tom De Bruyn, et al. Structure-based identification of OATP1B1/3 inhibitors. Mol Pharmacol. 2013 Jun;83(6):1257-67.

 Chemical & Physical Properties

Molecular Formula C32H52O2
Molecular Weight 468.75
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