3-O-Decyclopropyl Roflumilast

Modify Date: 2024-01-09 20:57:57

3-O-Decyclopropyl Roflumilast Structure
3-O-Decyclopropyl Roflumilast structure
Common Name 3-O-Decyclopropyl Roflumilast
CAS Number 1391052-76-8 Molecular Weight 349.117
Density 1.6±0.1 g/cm3 Boiling Point 397.4±42.0 °C at 760 mmHg
Molecular Formula C13H8Cl2F2N2O3 Melting Point N/A
MSDS N/A Flash Point 194.2±27.9 °C

 Use of 3-O-Decyclopropyl Roflumilast


Roflumilast Impurity E is the impurity of Roflumilast. Roflumilast(Daliresp) is a drug which acts as a selective and long-acting inhibitor of the enzyme PDE-4 with an IC50 value of 0.8 nM.

 Names

Name 3-O-Decyclopropyl Roflumilast
Synonym More Synonyms

 3-O-Decyclopropyl Roflumilast Biological Activity

Description Roflumilast Impurity E is the impurity of Roflumilast. Roflumilast(Daliresp) is a drug which acts as a selective and long-acting inhibitor of the enzyme PDE-4 with an IC50 value of 0.8 nM.
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 Chemical & Physical Properties

Density 1.6±0.1 g/cm3
Boiling Point 397.4±42.0 °C at 760 mmHg
Molecular Formula C13H8Cl2F2N2O3
Molecular Weight 349.117
Flash Point 194.2±27.9 °C
Exact Mass 347.988007
PSA 71.45000
LogP 3.37
Vapour Pressure 0.0±1.0 mmHg at 25°C
Index of Refraction 1.626
Storage condition 2-8℃

 Synonyms

Benzamide, N-(3,5-dichloro-4-pyridinyl)-4-(difluoromethoxy)-3-hydroxy-
N-(3,5-Dichloro-4-pyridinyl)-4-(difluoromethoxy)-3-hydroxybenzamide
N-(3,5-dichloropyridin-4-yl)-4-(difluoroMethoxy)-3-hydroxybenzaMide
3-(hydroxy)-N-(3,5-dichloro-4-pyridinyl) -4-difluoromethoxy) benzamide
Roflumilast Impurity E
Roflumilast Impurity 2
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Price: $132/1mg

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