Ghrelin agonist HM01
Modify Date: 2024-01-06 04:37:53
Ghrelin agonist HM01 structure
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Common Name | Ghrelin agonist HM01 | ||
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| CAS Number | 1394860-28-6 | Molecular Weight | 402.36 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C19H29Cl2N3O2 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of Ghrelin agonist HM01Ghrelin agonist HM01 is a novel potent, orally available ghrelin (GHS-R) agonist with Ki of 1.42 nM (human GHS-R1a), induces potent activation of intracellular calcium signaling with EC50 of 1.25 nM; mimics the neuronal effects of ghrelin in the arcuate nucleus and attenuates anorexia-cachexia syndrome in tumor-bearing rats, also attenuates cachexia in mice bearing bolon-26 (C26) tumors. |
| Name | Ghrelin agonist HM01 |
|---|
| Description | Ghrelin agonist HM01 is a novel potent, orally available ghrelin (GHS-R) agonist with Ki of 1.42 nM (human GHS-R1a), induces potent activation of intracellular calcium signaling with EC50 of 1.25 nM; mimics the neuronal effects of ghrelin in the arcuate nucleus and attenuates anorexia-cachexia syndrome in tumor-bearing rats, also attenuates cachexia in mice bearing bolon-26 (C26) tumors. |
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| References | References 1. Rudd JA, et al. Front Pharmacol. 2018 Aug 6;9:869. 2. Karasawa H, et al. Neurogastroenterol Motil. 2014 Dec;26(12):1771-82. 3. Villars FO, et al. Int J Mol Sci. 2017 May 5;18(5). pii: E986. View Related Products by Target Ghrelin Receptor (GHSR) |
| Molecular Formula | C19H29Cl2N3O2 |
|---|---|
| Molecular Weight | 402.36 |
- Shanghai Nianxing Industrial Co., Ltd
- China
- Product Name: Ghrelin agonist HM01
- Price: ￥Inquiry/1g
- Purity: 98.0%
- Delivery: 10 Day
- Contact: Huang
- Email: sales@echemcloud.com
- ShangHai DC Chemicals Co.,Ltd
- China
- Product Name: Ghrelin agonist HM01
- Price: ￥Inquiry/1g
- Purity: 98.9%
- Delivery: 1 Day
- Contact: Tony Lai
- Email: order@dcchemicals.com
- DC Chemicals Limited
- China
- Product Name: Ghrelin agonist HM01
- Price: $Inquiry/1g
- Purity: 98.0%
- Delivery: 3 Day
- Contact: Tony Cao
- Email: sales@dcchemicals.com
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