Isodunnianol structure
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Common Name | Isodunnianol | ||
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CAS Number | 139726-30-0 | Molecular Weight | 398.493 | |
Density | 1.1±0.1 g/cm3 | Boiling Point | 511.2±50.0 °C at 760 mmHg | |
Molecular Formula | C27H26O3 | Melting Point | N/A | |
MSDS | N/A | Flash Point | 263.0±30.1 °C |
Use of IsodunnianolIsodunnianol is a autophagy inducer. Isodunnianol induces autophagy and increases he expression of pAMPK172, pULK1555,decreases teh expression of pULK1757, SQSTM2. Isodunnianol decreases Doxorubicin (HY-15142A)-induced cardiotoxicity[1]. |
Name | 5,5'-Diallyl-3-(4-allylphenoxy)-2,2'-biphenyldiol |
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Synonym | More Synonyms |
Description | Isodunnianol is a autophagy inducer. Isodunnianol induces autophagy and increases he expression of pAMPK172, pULK1555,decreases teh expression of pULK1757, SQSTM2. Isodunnianol decreases Doxorubicin (HY-15142A)-induced cardiotoxicity[1]. |
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Related Catalog | |
In Vitro | Isodunnianol (10 µM; 6, 24 h) 在 H9C2 细胞中诱导自噬并增加 pAMPK172、pULK1555 的表达,降低 pULK1757、SQSTM2 的表达[1]。 Cell Autophagy Assay[1] Cell Line: H9C2 cells Concentration: 10 µM Incubation Time: 6, 24 h Result: Induced autophagic. Western Blot Analysis[1] Cell Line: H9C2 cells Concentration: 10 µM Incubation Time: 6, 24 h Result: Significantly increased the expression of pAMPK172, pULK1555,decreased teh expression of pULK1757, SQSTM2 in a time-dependent manner. |
References |
Density | 1.1±0.1 g/cm3 |
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Boiling Point | 511.2±50.0 °C at 760 mmHg |
Molecular Formula | C27H26O3 |
Molecular Weight | 398.493 |
Flash Point | 263.0±30.1 °C |
Exact Mass | 398.188202 |
PSA | 49.69000 |
LogP | 6.74 |
Vapour Pressure | 0.0±1.4 mmHg at 25°C |
Index of Refraction | 1.607 |
Hazard Codes | Xi |
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Isodunnianol |
12-Hydroxy-drim-8-en-11-saeure-lacton |
12-hydroxy-drim-8-en-11-oic acid-lactone |
5,5'-Diallyl-3-(4-allylphenoxy)-2,2'-biphenyldiol |
Isodrimenin |
isoduinnianol |
[1,1'-Biphenyl]-2,2'-diol, 5,5'-di-2-propen-1-yl-3-[4-(2-propen-1-yl)phenoxy]- |
MEGPFBRAROUGQD-NHYWBVRUSA |
Isodrimenine |