Palbinone

Modify Date: 2024-01-13 17:26:10

Palbinone Structure
Palbinone structure
Common Name Palbinone
CAS Number 139954-00-0 Molecular Weight 358.47
Density 1.2±0.1 g/cm3 Boiling Point 508.5±50.0 °C at 760 mmHg
Molecular Formula C22H30O4 Melting Point N/A
MSDS N/A Flash Point 275.4±26.6 °C

 Use of Palbinone


Palbinone is a terpenoid isolated from the roots of Paeonia albiflora Pallas, potently inhibits 3α-hydroxysteroid dehydrogenase (3α-HSD), with an IC50 of 46 nM. Anti-inflammatory activity[1].

 Names

Name Palbinone
Synonym More Synonyms

 Palbinone Biological Activity

Description Palbinone is a terpenoid isolated from the roots of Paeonia albiflora Pallas, potently inhibits 3α-hydroxysteroid dehydrogenase (3α-HSD), with an IC50 of 46 nM. Anti-inflammatory activity[1].
Related Catalog
Target

IC50: 46 nM (3α-HSD)[1]

References

[1]. Kadota S, et al. Palbinone, a novel terpenoid from Paeonia albiflora; potent inhibitory activity on 3 alpha-hydroxysteroid dehydrogenase. Chem Pharm Bull (Tokyo). 1993 Mar;41(3):487-90.

 Chemical & Physical Properties

Density 1.2±0.1 g/cm3
Boiling Point 508.5±50.0 °C at 760 mmHg
Molecular Formula C22H30O4
Molecular Weight 358.47
Flash Point 275.4±26.6 °C
Exact Mass 358.214417
PSA 74.60000
LogP 3.35
Vapour Pressure 0.0±3.0 mmHg at 25°C
Index of Refraction 1.586

 Synonyms

18-Norandrosta-11,13(17)-diene-15,16-dione, 3,17-dihydroxy-4,4,8,14-tetramethyl-, (3β,5α)-
Gona-11,13(17)-diene-15,16-dione, 3,17-dihydroxy-4,4,8,10,14-pentamethyl-, (3β,5α)-
(3β,5α)-3,17-Dihydroxy-4,4,8,10,14-pentamethylgona-11,13(17)-diene-15,16-dione
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