(R)-Praziquantel D11

Modify Date: 2024-01-22 10:37:48

(R)-Praziquantel D11 Structure
(R)-Praziquantel D11 structure
Common Name (R)-Praziquantel D11
CAS Number 1399880-38-6 Molecular Weight 323.47
Density N/A Boiling Point N/A
Molecular Formula C19H13D11N2O2 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of (R)-Praziquantel D11


(R)-Praziquantel D11 is the deuterium labeled (R)-Praziquantel. (R)-Praziquantel, the active enantiomer of Praziquantel, is a partial agonist of the human 5-HT2B receptor. (R)-Praziquantel acts as an antischistosomal eutomer[1].

 Names

Name (R)-Praziquantel D11

 (R)-Praziquantel D11 Biological Activity

Description (R)-Praziquantel D11 is the deuterium labeled (R)-Praziquantel. (R)-Praziquantel, the active enantiomer of Praziquantel, is a partial agonist of the human 5-HT2B receptor. (R)-Praziquantel acts as an antischistosomal eutomer[1].
Related Catalog
Target

5-HT2B Receptor

Antischistosomal

In Vitro (R)-Praziquantel ((R)-PZQ) is a G-protein-coupled receptor ligand. (R)-Praziquantel modulation of serotoninergic signaling occurs over a concentration range sufficient to regulate vascular tone of the mesenteric blood vessels where the adult parasites reside within their host. The important anthelmintic is supported by a broad, cross species polypharmacology with (R)-Praziquantel modulating signaling events in both host and parasite[1].
References

[1]. Chan JD, et al. The anthelmintic praziquantel is a human serotoninergic G-protein-coupled receptor ligand. Nat Commun. 2017 Dec 5;8(1):1910.

 Chemical & Physical Properties

Molecular Formula C19H13D11N2O2
Molecular Weight 323.47
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