Afatinib impurity 11

Modify Date: 2024-01-14 09:48:58

Afatinib impurity 11 structure	Common Name	Afatinib impurity 11
	CAS Number	1402086-20-7	Molecular Weight	428.84
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₁H₁₈ClFN₄O₃	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of Afatinib impurity 11

Afatinib impurity 11 is an impurity of Afatinib. Afatinib is an irreversible EGFR family inhibitor with IC50s of 0.5 nM, 0.4 nM, 10 nM and 14 nM for EGFRwt, EGFRL858R, EGFRL858R/T790M and HER2, respectively[1].

Name	Afatinib impurity 11

Description	Afatinib impurity 11 is an impurity of Afatinib. Afatinib is an irreversible EGFR family inhibitor with IC50s of 0.5 nM, 0.4 nM, 10 nM and 14 nM for EGFRwt, EGFRL858R, EGFRL858R/T790M and HER2, respectively[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> JAK/STAT Signaling >> EGFR Signaling Pathways >> Protein Tyrosine Kinase/RTK >> EGFR Signaling Pathways >> Autophagy >> Autophagy
References	[1]. Li D, et al. BIBW2992, an irreversible EGFR/HER2 inhibitor highly effective in preclinical lung cancer models. Oncogene. 2008 Aug 7;27(34):4702-11.

Molecular Formula	C₂₁H₁₈ClFN₄O₃
Molecular Weight	428.84

Shanghai Nianxing Industrial Co., Ltd
China
Product Name: Afatinib impurity 11
Price: Negotiable
Purity: 99.0%
Delivery: 10 Day
Contact: Huang
Email: sales@echemcloud.com

DC Chemicals Limited
China
Product Name: Afatinib impurity 11
Price: $Inquiry/250mg $Inquiry/100mg $Inquiry/1g
Purity: 98.0%
Delivery: 3 Day
Contact: Tony Cao
Email: sales@dcchemicals.com

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