RSVA 405

Modify Date: 2024-04-09 18:37:11

RSVA 405 Structure
RSVA 405 structure
Common Name RSVA 405
CAS Number 140405-36-3 Molecular Weight 312.36600
Density N/A Boiling Point N/A
Molecular Formula C17H20N4O2 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of RSVA 405


RSVA405 is a potent, orally active activator of AMPK, with an EC50 of 1 μM. RSVA405 facilitates CaMKKβ-dependent activation of AMPK, inhibits mTOR, and promotes autophagy to increase Aβ degradation. RSVA405 has anti-inflammatory effects through the inhibition of STAT3 function. RSVA405 also can be used for the research of obesity.

 Names

Name N'-[1-(4-diethylamino-2-hydroxyphenyl)methylidene]isonicotinohydrazide
Synonym More Synonyms

 Chemical & Physical Properties

Molecular Formula C17H20N4O2
Molecular Weight 312.36600
Exact Mass 312.15900
PSA 77.82000
LogP 2.78820

 Synonyms

p-(N,N-diethylamino)salicylaldehyde isonicotinoylhydrazone
N'-[4-(diethylamino)-2-hydroxybenzylidene]isonicotinohydrazide
Hit2Lead 5113025
ST 91