Bacitracin zinc
Modify Date: 2024-01-02 10:56:24
Bacitracin zinc structure
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Common Name | Bacitracin zinc | ||
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| CAS Number | 1405-89-6 | Molecular Weight | 1488.101 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C66H101N17O16SZn | Melting Point | 250 ºC (dec.) | |
| MSDS | Chinese USA | Flash Point | N/A | |
Use of Bacitracin zincBacitracin Zinc is a dephosphorylation of the C55-isoprenyl pyrophosphate interference for inhibition of cleavage of Tyr from Met-enkephalin with IC50 of 10 μM.Target: AntibacterialBacitracin is a mixture of related cyclic polypeptides produced by organisms of the licheniformis group of Bacillus subtilis var Tracy. Its unique name derives from the fact that the bacillus producing it was first isolated in 1943 from a knee scrape from a girl named Margaret Tracy. As a toxic and difficult-to-use antibiotic, bacitracin doesn't work well orally. However, it is very effective topically. Bacitracin is synthesised via the so-called nonribosomal peptide synthetases (NRPSs), which means that ribosomes are not involved in its synthesis [1, 2]. |
| Name | Zinc bacitracin |
|---|---|
| Synonym | More Synonyms |
| Description | Bacitracin Zinc is a dephosphorylation of the C55-isoprenyl pyrophosphate interference for inhibition of cleavage of Tyr from Met-enkephalin with IC50 of 10 μM.Target: AntibacterialBacitracin is a mixture of related cyclic polypeptides produced by organisms of the licheniformis group of Bacillus subtilis var Tracy. Its unique name derives from the fact that the bacillus producing it was first isolated in 1943 from a knee scrape from a girl named Margaret Tracy. As a toxic and difficult-to-use antibiotic, bacitracin doesn't work well orally. However, it is very effective topically. Bacitracin is synthesised via the so-called nonribosomal peptide synthetases (NRPSs), which means that ribosomes are not involved in its synthesis [1, 2]. |
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| Related Catalog | |
| References |
| Melting Point | 250 ºC (dec.) |
|---|---|
| Molecular Formula | C66H101N17O16SZn |
| Molecular Weight | 1488.101 |
| Exact Mass | 1485.677002 |
| Storage condition | 2-8°C |
| Water Solubility | 5.1 g/L (28 ºC) |
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Clearance of nasal Staphylococcus aureus colonization with triple antibiotic ointment.
Journal. of. Drugs in. Dermatology. 11(12) , 1490-2, (2012) The prevalence of Staphylococcus aureus colonization of healthcare workers is reported at 30%, with colonization rates for methicillin-resistant S aureus (MRSA) reported between 2.0% and 8.5% among in... |
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Role of topical antibiotic prophylaxis in prevention of bacterial translocation into upper trachea in nasally intubated patients undergoing tonsillectomies.
Int. J. Pediatr. Otorhinolaryngol. 77(2) , 270-4, (2013) The human oropharynx and nasopharynx are home of different bacteria and fungi. The initial sterile endotracheal tube (ETT) transfers mechanically the bacteria from the nasopharynx and oropharynx to th... |
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Alteration of bile acid metabolism in pseudo germ-free rats [corrected].
Arch. Pharm. Res. 35(11) , 1969-77, (2012) To characterize the impact of gut microbiota on host bile acid metabolism, we investigated the metabolic profiles of oxysterols and bile acids (BAs) in a conventional rat model (SD) (n=5) and its pseu... |
| Bacitracin zinc |
| EINECS 215-787-8 |
| L-isoleucinamide, N-[[2-(1-amino-2-methylbutyl)-4,5-dihydro-4-thiazolyl]carbonyl]-L-leucyl-D-α-glutamyl-N-[(3S,6R,9S,12R,15S,18R,21S)-3-(2-amino-2-oxoethyl)-18-(3-aminopropyl)-6-(carboxymethyl)-9- |
| Bacitracin zinc salt |
| MFCD00130598 |
| L-isoleucinamide, N-[[2-(1-amino-2-methylbutyl)-4,5-dihydro-4-thiazolyl]carbonyl]-L-leucyl-D-α-glutamyl-N-[(3S,6R,9S,12R,15S,18R,21S)-3-(2-amino-2-oxoethyl)-18-(3-aminopropyl)-6-(carboxymethyl)-9-(1H-imidazol-5-ylmethyl)-15-(1-methylpropyl)-2,5,8,11,14,17,20-heptaoxo-12-(phenylmethyl)-1,4,7,10,13,16,19-heptaazacyclopentacos-21-yl]-, zinc salt (1:1) |
| L-Isoleucinamide, N-[[2-(1-amino-2-methylbutyl)-4,5-dihydro-4-thiazolyl]carbonyl]-L-leucyl-D-α-glutamyl-N-[(3S,6R,9S,12R,15S,18R,21S)-3-(2-amino-2-oxoethyl)-18-(3-aminopropyl)-6-(carboxymethyl)-9- (1H-imidazol-5-ylmethyl)-15-(1-methylpropyl)-2,5,8,11,14,17,20-heptaoxo-12-(phenylmethyl)-1,4,7,10,13,16,19-heptaazacyclopentacos-21-yl]-, zinc salt (1:1) |
| Bacitracin (Zinc) |
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