Filaminast

Modify Date: 2024-03-01 12:00:53

Filaminast Structure
Filaminast structure
Common Name Filaminast
CAS Number 141184-34-1 Molecular Weight 292.33000
Density 1.25g/cm3 Boiling Point 432.1ºC at 760mmHg
Molecular Formula C15H20N2O4 Melting Point N/A
MSDS N/A Flash Point 215.1ºC

 Use of Filaminast


WAY-PDA 641 is a potent and preferential PDE-IV inhibitor, with an IC50 of 0.42 μM for canine trachealis PDE-IV. WAY-PDA 641 induces respiratory muscle relaxation and bronchodilation[1].

 Names

Name [(E)-1-(3-cyclopentyloxy-4-methoxyphenyl)ethylideneamino] carbamate
Synonym More Synonyms

 Filaminast Biological Activity

Description WAY-PDA 641 is a potent and preferential PDE-IV inhibitor, with an IC50 of 0.42 μM for canine trachealis PDE-IV. WAY-PDA 641 induces respiratory muscle relaxation and bronchodilation[1].
Related Catalog
References

[1]. Heaslip RJ, et, al. Phosphodiesterase-IV inhibition, respiratory muscle relaxation and bronchodilation by WAY-PDA-641. J Pharmacol Exp Ther. 1994 Feb;268(2):888-96.  

 Chemical & Physical Properties

Density 1.25g/cm3
Boiling Point 432.1ºC at 760mmHg
Molecular Formula C15H20N2O4
Molecular Weight 292.33000
Flash Point 215.1ºC
Exact Mass 292.14200
PSA 84.13000
LogP 3.34970
Vapour Pressure 0mmHg at 25°C
Index of Refraction 1.566

 Synonyms

Filaminast (USAN/INN)
FIL
Way-pda-641
(1E)-1-[3-(CYCLOPENTYLOXY)-4-METHOXYPHENYL]ETHANONE O-(AMINOCARBONYL)OXIME
FILAMINAST
UNII-CDD69JC61J
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