LY 293284

Modify Date: 2024-02-09 11:41:35

LY 293284 Structure
LY 293284 structure
Common Name LY 293284
CAS Number 141318-62-9 Molecular Weight 298.42
Density 1.11g/cm3 Boiling Point 478.2ºC at 760mmHg
Molecular Formula C19H26N2O Melting Point N/A
MSDS N/A Flash Point 243ºC

 Use of LY 293284


LY 293284 is a potent and selective 5-HT1A receptor agonist. LY 293284 results in a significant drop in core temperature and consumes more food in cholestasis rat induced by bile duct resection[1][2].

 Names

Name 1-[(4R)-4-(dipropylamino)-1,3,4,5-tetrahydrobenzo[cd]indol-6-yl]ethanone
Synonym More Synonyms

 LY 293284 Biological Activity

Description LY 293284 is a potent and selective 5-HT1A receptor agonist. LY 293284 results in a significant drop in core temperature and consumes more food in cholestasis rat induced by bile duct resection[1][2].
Related Catalog
References

[1]. Marona-Lewicka D, et al. Aripiprazole (OPC-14597) fully substitutes for the 5-HT1A receptor agonist LY293284 in the drug discrimination assay in rats. Psychopharmacology (Berl). 2004;172(4):415-421.  

[2]. Burak KW, et al. Increased midbrain 5-HT1A receptor number and responsiveness in cholestatic rats. Brain Res. 2001;892(2):376-379.  

 Chemical & Physical Properties

Density 1.11g/cm3
Boiling Point 478.2ºC at 760mmHg
Molecular Formula C19H26N2O
Molecular Weight 298.42
Flash Point 243ºC
Exact Mass 298.20500
PSA 36.10000
LogP 3.95970
Vapour Pressure 2.63E-09mmHg at 25°C
Index of Refraction 1.595

 Synonyms

Ethanone,1-(4-(dipropylamino)-1,3,4,5-tetrahydrobenz(cd)indol-6-yl)-,(R)
6-Acetyl-4-(di-n-propylamino)-1,3,4,5-tetrahydrobenz(c,d)indole
C19H26N2O
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